HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~TIP49
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 456
+	Hs
		892123 ACTB_HUMAN (4-377): 0: 599: 94.12		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Hs
		930058 ACTG_HUMAN (4-377): 0: 599: 94.39		RUVB1_HUMAN (1-456): 0: 704: 100.00
+	Dm
		501453 ACT5_DROME (1-377): 0: 598: 93.10		RUVB1_DROME (1-455): 0: 660: 79.56
+	Hs
		892121 ACTB_HUMAN (4-377): 0: 599: 94.12		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		930057 ACTG_HUMAN (4-377): 0: 599: 94.39		RUVB2_HUMAN (2-455): 0: 651: 42.76
+	Hs
		932462 ACTC_HUMAN (1-377): 0: 599: 100.00		RUVB2_HUMAN (2-455): 0: 651: 42.76