Protein: KAD1
Adenylate kinase isoenzyme 1 (AK 1) (EC 2.7.4.3) (EC 2.7.4.4) (EC 2.7.4.6) (ATP-AMP transphosphorylase 1) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) (Myokinase)

Gene: KAD1, AK1
Organism: Homo sapiens
Interactions: 58
UniProt ID: P00568

Gene Ontology (top 5):
GO:0001520 - outer dense fiber
GO:0004017 - AMP kinase activity
GO:0004550 - nucleoside diphosphate kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

365738

TAU
Microtubule-associated protein tau

2

4

High-throughput

0.601

High

365736

A4
Amyloid-beta precursor protein

2

1

Small-scale

0.595

High

365754

HNRPU
Heterogeneous nuclear ribonucleoprotein U

2

0

High-throughput

0.576

High

365743

T2EB
Transcription initiation factor IIE subunit beta

1

1

High-throughput

0.536

High

365760

COBL1
Cordon-bleu protein-like 1

1

1

High-throughput

0.536

High

365781

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.536

High

259277

BRD4
Bromodomain-containing protein 4

2

1

Small-scale

0.533

High

365750

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.529

High

365777

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.529

High

365766

KMT2C
Histone-lysine N-methyltransferase 2C

1

3

High-throughput

0.515

High

60286

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.513

High

185331

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.513

High

321805

PCF11
Pre-mRNA cleavage complex 2 protein Pcf11

1

0

High-throughput

0.513

High

335757

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.513

High

365751

S12A2
Solute carrier family 12 member 2

1

0

High-throughput

0.513

High

365758

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

0

High-throughput

0.513

High

365768

GEMI5
Gem-associated protein 5

1

0

High-throughput

0.513

High

365772

SUCB2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.513

High

365775

VAMP8
Vesicle-associated membrane protein 8

1

0

High-throughput

0.513

High

365753

HTRA4
Serine protease HTRA4

1

1

High-throughput

0.489

High

365763

RFIP2
Rab11 family-interacting protein 2

1

2

High-throughput

0.489

High

365764

KDM3B
Lysine-specific demethylase 3B

1

1

High-throughput

0.489

High

365773

BUD13
BUD13 homolog

1

2

High-throughput

0.489

High

365770

TRI63
E3 ubiquitin-protein ligase TRIM63

1

8

Small-scale

0.481

High

240431

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

365737

HS90B
Heat shock protein HSP 90-beta

1

3

High-throughput

0.479

High

365740

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

365744

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

1

High-throughput

0.479

High

365746

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

365747

MDHC
Malate dehydrogenase, cytoplasmic

1

3

High-throughput

0.479

High

365748

MRE11
Double-strand break repair protein MRE11

1

1

High-throughput

0.479

High

365757

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

365762

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

365776

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.479

High

365778

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

365739

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.458

High

365749

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

365752

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.458

High

365780

RBGP1
Rab GTPase-activating protein 1

1

0

High-throughput

0.458

High

107421

F8W8I6
Cytotoxic granule associated RNA binding protein TIA1

1

1

High-throughput

0.445

High

346581

TTC4
Tetratricopeptide repeat protein 4

1

2

High-throughput

0.445

High

365741

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.445

High

365742

ANFB
Natriuretic peptides B

1

1

High-throughput

0.445

High

365745

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

Small-scale

0.445

High

365755

MFGM
Lactadherin

1

1

High-throughput

0.445

High

105057

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

107414

F8W7U8
Double-strand break repair protein

1

1

High-throughput

0.407

High

261036

NSMA
Sphingomyelin phosphodiesterase 2

1

1

High-throughput

0.407

High

365769

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

1

High-throughput

0.407

High

365774

TINF2
TERF1-interacting nuclear factor 2

1

0

High-throughput

0.288

High

365759

T4S20
Transmembrane 4 L6 family member 20

1

0

High-throughput

0.279

Low

365761

B3GLT
Beta-1,3-glucosyltransferase

1

0

High-throughput

0.279

Low

365765

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

0

High-throughput

0.279

Low

365767

OR2K2
Olfactory receptor 2K2

1

0

High-throughput

0.279

Low

365771

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

0

High-throughput

0.279

Low

365756

FHL2
Four and a half LIM domains protein 2

1

0

Small-scale

0.261

Low

365735

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

365779

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025