HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17606992
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007015 - actin filament organization GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 639
+	Hs
		892142 ACTB_HUMAN (4-377): 0: 599: 94.12		CD2AP_HUMAN (1-639): 9.29e-139: 420: 100.00
+	Hs
		932316 ACTC_HUMAN (1-377): 0: 599: 100.00		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		253332 ACTB_HUMAN (4-377): 0: 599: 94.12		SRGP2_HUMAN (2-443): 3.56e-43: 169: 11.52
+	Hs
		891671 ACTB_HUMAN (4-377): 0: 599: 94.12		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		924453 ACTG_HUMAN (4-377): 0: 599: 94.39		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		924456 ACTC_HUMAN (1-377): 0: 599: 100.00		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		924454 ACTH_HUMAN (4-377): 0: 591: 98.93		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		933003 ACTS_HUMAN (1-377): 0: 599: 98.94		DNMBP_HUMAN (113-602): 4.85e-17: 87.7: 15.23
+	Hs
		235496 ACTS_HUMAN (1-377): 0: 599: 98.94		VINEX_HUMAN (163-343): 4.52e-13: 74.2: 18.28
+	Hs
		891821 ACTB_HUMAN (4-377): 0: 599: 94.12		SH319_HUMAN (75-368): 3.05e-10: 65.4: 17.45