Protein: HOS4
Protein HOS4

Gene: HOS4
Organism: Saccharomyces cerevisiae S288C
Interactions: 42
UniProt ID: P40480

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006338 - chromatin remodeling
GO:0006974 - DNA damage response
GO:0009267 - cellular response to starvation
GO:0034967 - Set3 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

796839

SIF2
SIR4-interacting protein SIF2

8

15

Small-scale

0.752

High

781750

SET3
SET domain-containing protein 3

7

3

Small-scale

0.742

High

364577

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.724

High

672767

SNT1
Probable DNA-binding protein SNT1

5

9

Small-scale

0.714

High

575955

CYPH
Peptidyl-prolyl cis-trans isomerase

5

4

Small-scale

0.712

High

825202

HOS2
Probable histone deacetylase HOS2

4

11

Small-scale

0.687

High

825204

HST1
NAD-dependent protein deacetylase HST1

4

8

Small-scale

0.687

High

441156

KAPA
cAMP-dependent protein kinase type 1

1

3

High-throughput

0.647

High

448742

SNF1
Carbon catabolite-derepressing protein kinase

1

2

High-throughput

0.647

High

602497

PHO85
Cyclin-dependent protein kinase PHO85

1

3

High-throughput

0.647

High

825199

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

2

High-throughput

0.647

High

545136

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

High-throughput

0.601

High

825201

ZDS1
Protein ZDS1

2

6

High-throughput

0.567

High

524168

HSP71
Heat shock protein SSA1

2

10

High-throughput

0.552

High

825206

LSM7
LSM complex subunit LSM7

1

1

High-throughput

0.508

High

585498

KCY
Uridylate kinase

1

1

High-throughput

0.479

High

707293

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

805546

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

4

Small-scale

0.479

High

825211

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

816064

ACA1
ATF/CREB activator 1

1

0

High-throughput

0.460

High

576068

AROF
Phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited

1

0

High-throughput

0.458

High

763909

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

795722

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.458

High

825209

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

825210

TOS4
Protein TOS4

1

0

High-throughput

0.458

High

825212

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

526871

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

597161

BIP
Endoplasmic reticulum chaperone BiP

1

14

High-throughput

0.445

High

676061

MAS5
Mitochondrial protein import protein MAS5

1

9

High-throughput

0.445

High

741716

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.445

High

825203

PBP1
PAB1-binding protein 1

1

2

High-throughput

0.445

High

825200

KEL2
Kelch repeat-containing protein 2

1

2

High-throughput

0.439

High

793607

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

3

High-throughput

0.437

High

825207

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

810957

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.407

High

825208

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.251

Low

825214

YH41A
Transposon Ty4-H Gag polyprotein

1

0

High-throughput

0.251

Low

723614

MLS1
Malate synthase 1

1

0

High-throughput

0.249

Low

751547

DHE2
NAD-specific glutamate dehydrogenase

1

0

High-throughput

0.249

Low

825198

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

825205

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low

825213

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025