HitPredict

Interactor 1: D4A9W4 (D4A9W4)
IKAROS family zinc finger 1
Gene: Ikzf1

Interactor 2: CTBP1 (Q9Z2F5)
C-terminal-binding protein 1 (CtBP1) (EC 1.1.1.-) (50 kDa BFA-dependent ADP-ribosylation substrate) (BARS-50) (C-terminal-binding protein 3) (CtBP3)
Gene: CTBP1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22301782
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0019904 - protein domain specific binding GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 534 Rn			1 430
+	Hs
		941426 IKZF1_HUMAN (1-534): 0: 602: 89.05		CTBP2_HUMAN (3-429): 0: 545: 80.56
+	Hs
		1103145 IKZF1_HUMAN (1-534): 0: 602: 89.05		CTBP1_HUMAN (3-430): 0: 530: 98.36
+	Hs
		941600 IKZF2_HUMAN (43-532): 1.27e-131: 394: 52.06		CTBP2_HUMAN (3-429): 0: 545: 80.56
+	Hs
		941601 IKZF3_HUMAN (129-533): 7.56e-130: 389: 61.71		CTBP2_HUMAN (3-429): 0: 545: 80.56
+	Hs
		1103368 IKZF4_HUMAN (58-530): 4.92e-133: 400: 51.19		CTBP1_HUMAN (3-430): 0: 530: 98.36
+	Hs
		1103436 IKZF2_HUMAN (43-532): 1.27e-131: 394: 52.06		CTBP1_HUMAN (3-430): 0: 530: 98.36
+	Mm
		941636 Q8C5P6_MOUSE (326-527): 7.69e-09: 58.7: 14.78		CTBP2_MOUSE (3-429): 0: 542: 80.33
+	Mm
		312882 Q8C5P6_MOUSE (326-527): 7.69e-09: 58.7: 14.78		CTBP1_MOUSE (3-430): 0: 538: 99.77