Protein: IKZF2
Zinc finger protein Helios (Ikaros family zinc finger protein 2)

Gene: IKZF2
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q9UKS7

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1104695

IKZF1
DNA-binding protein Ikaros

5

16

Small-scale

0.919

High

1461211

IKZF3
Zinc finger protein Aiolos

2

16

Small-scale

0.754

High

1165325

LONF1
LON peptidase N-terminal domain and RING finger protein 1

1

10

High-throughput

0.740

High

1116120

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.691

High

1434727

IKZF5
Zinc finger protein Pegasus

2

14

High-throughput

0.628

High

1461210

IKZF2
Zinc finger protein Helios

1

15

Small-scale

0.618

High

1331117

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

7

High-throughput

0.606

High

715978

AQP1
Aquaporin-1

1

2

High-throughput

0.573

High

941600

CTBP2
C-terminal-binding protein 2

1

9

High-throughput

0.573

High

1103436

CTBP1
C-terminal-binding protein 1

1

9

High-throughput

0.541

High

857587

NOTC1
Neurogenic locus notch homolog protein 1

1

20

High-throughput

0.536

High

1110173

HDAC1
Histone deacetylase 1

1

13

High-throughput

0.536

High

564541

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

1208909

H2B2F
Histone H2B type 2-F

1

4

High-throughput

0.515

High

941085

HDAC4
Histone deacetylase 4

1

20

Small-scale

0.501

High

274397

SIN3B
Paired amphipathic helix protein Sin3b

1

7

Small-scale

0.479

High

340950

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

6

High-throughput

0.479

High

1106392

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

6

High-throughput

0.479

High

1119537

PEBB
Core-binding factor subunit beta

1

2

High-throughput

0.479

High

1133040

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

11

Small-scale

0.479

High

1368198

HDAC2
Histone deacetylase 2

1

13

Small-scale

0.479

High

1403047

SIN3A
Paired amphipathic helix protein Sin3a

1

7

Small-scale

0.479

High

1461212

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

1

Small-scale

0.479

High

1461213

HDAC5
Histone deacetylase 5

1

20

Small-scale

0.479

High

373456

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.445

High

1400178

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025