Protein: PSB4
Proteasome subunit beta type-4 (Macropain subunit C11) (Multicatalytic endopeptidase complex subunit C11) (Proteasome component C11) (Proteinase YSCE subunit 11)

Gene: PSB4, PRE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 131
UniProt ID: P22141

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604803

PSA4
Proteasome subunit alpha type-4

19

20

Small-scale

0.987

High

597195

PSA7
Probable proteasome subunit alpha type-7

19

20

Small-scale

0.987

High

604764

PSB5
Proteasome subunit beta type-5

17

20

Small-scale

0.984

High

604775

PRS7
26S proteasome regulatory subunit 7 homolog

16

20

Small-scale

0.982

High

604752

PSA2
Proteasome subunit alpha type-2

15

20

Small-scale

0.982

High

604751

PSA3
Proteasome subunit alpha type-3

14

20

Small-scale

0.981

High

604767

PSA5
Proteasome subunit alpha type-5

14

20

Small-scale

0.981

High

604802

PSA6
Proteasome subunit alpha type-6

14

20

Small-scale

0.981

High

604765

PSB7
Proteasome subunit beta type-7

14

20

Small-scale

0.980

High

597282

PSA1
Proteasome subunit alpha type-1

13

20

Small-scale

0.979

High

604790

PSB1
Proteasome subunit beta type-1

13

20

Small-scale

0.978

High

604755

PSB3
Proteasome subunit beta type-3

13

20

Small-scale

0.977

High

604753

PSB6
Proteasome subunit beta type-6

12

20

Small-scale

0.975

High

604754

PSB2
Proteasome subunit beta type-2

10

20

Small-scale

0.966

High

604826

PRS8
26S proteasome regulatory subunit 8 homolog

9

20

Small-scale

0.963

High

604784

UMP1
Proteasome maturation factor UMP1

8

3

Small-scale

0.958

High

604773

PRS6A
26S proteasome regulatory subunit 6A

6

20

Small-scale

0.935

High

604819

PRS10
26S proteasome subunit RPT4

5

20

Small-scale

0.906

High

604774

PRS6B
26S proteasome regulatory subunit 6B homolog

4

20

Small-scale

0.881

High

604804

PRS4
26S proteasome regulatory subunit 4 homolog

4

20

Small-scale

0.881

High

604844

RPN6
26S proteasome regulatory subunit RPN6

4

20

Small-scale

0.881

High

604747

PSB4
Proteasome subunit beta type-4

4

20

Small-scale

0.867

High

604806

BLM10
Proteasome activator BLM10

4

10

Small-scale

0.866

High

604832

POC1
Proteasome chaperone 1

6

3

Small-scale

0.836

High

604807

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

13

20

Small-scale

0.755

High

604758

CDC48
Cell division control protein 48

2

6

Small-scale

0.754

High

604843

RPN5
26S proteasome regulatory subunit RPN5

10

20

Small-scale

0.754

High

604798

RPN10
26S proteasome regulatory subunit RPN10

10

13

Small-scale

0.753

High

604768

RPN12
26S proteasome regulatory subunit RPN12

9

7

Small-scale

0.750

High

604840

RPN8
26S proteasome regulatory subunit RPN8

9

19

Small-scale

0.747

High

604778

POC2
Proteasome assembly chaperone 2

7

3

Small-scale

0.741

High

604794

RPN1
26S proteasome regulatory subunit RPN1

6

20

Small-scale

0.724

High

604800

RPN3
26S proteasome regulatory subunit RPN3

5

9

Small-scale

0.706

High

604772

RAD23
UV excision repair protein RAD23

4

20

Small-scale

0.699

High

141825

RPN13
26S proteasome regulatory subunit RPN13

4

2

Small-scale

0.683

High

604769

RPN2
26S proteasome regulatory subunit RPN2

4

20

Small-scale

0.683

High

604828

RPN9
26S proteasome regulatory subunit RPN9

4

12

Small-scale

0.683

High

604835

RPN7
26S proteasome regulatory subunit RPN7

4

20

Small-scale

0.683

High

490352

HSP71
Heat shock protein SSA1

4

13

Small-scale

0.676

High

604808

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

4

14

Small-scale

0.676

High

604814

PSD10
Probable 26S proteasome regulatory subunit p28

3

2

Small-scale

0.651

High

294093

SEM1
26S proteasome complex subunit SEM1

3

2

Small-scale

0.650

High

367743

EF1A
Elongation factor 1-alpha

3

1

Small-scale

0.646

High

604793

ECM29
Proteasome component ECM29

3

9

Small-scale

0.640

High

604829

PDS5
Sister chromatid cohesion protein PDS5

2

2

Small-scale

0.620

High

604839

POC3
Proteasome chaperone 3

1

1

Small-scale

0.618

High

604842

POC4
Proteasome chaperone 4

1

1

Small-scale

0.618

High

477128

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

20

Small-scale

0.584

High

493212

HSP72
Heat shock protein SSA2

2

14

Small-scale

0.584

High

543205

HSC82
ATP-dependent molecular chaperone HSC82

2

6

Small-scale

0.584

High

604812

DSK2
Ubiquitin domain-containing protein DSK2

2

20

Small-scale

0.584

High

549786

UBC4
Ubiquitin-conjugating enzyme E2 4

2

5

Small-scale

0.571

High

604801

SSB2
Ribosome-associated molecular chaperone SSB2

2

14

Small-scale

0.571

High

604792

YHJ3
Uncharacterized protein YHR033W

1

1

High-throughput

0.536

High

604820

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

604757

FUB1
Silencing boundary-establishment protein FUB1

2

3

Small-scale

0.533

High

604750

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

3

High-throughput

0.515

High

604761

CIN8
Kinesin-like protein CIN8

1

1

High-throughput

0.515

High

604817

TOS8
Homeobox protein TOS8

1

1

High-throughput

0.515

High

587932

HSP60
Heat shock protein 60, mitochondrial

1

6

High-throughput

0.500

High

604786

HSM3
DNA mismatch repair protein HSM3

1

1

Small-scale

0.500

High

604818

RPN14
26S proteasome regulatory subunit RPN14

1

3

Small-scale

0.500

High

523340

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.493

High

604785

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

Small-scale

0.493

High

604791

SIC1
Protein SIC1

1

0

Small-scale

0.480

High

343532

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.479

High

378286

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.479

High

498438

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.479

High

554553

HSP26
Heat shock protein 26

1

0

High-throughput

0.479

High

342856

ENO2
Enolase 2

1

1

Small-scale

0.479

High

355351

H2B1
Histone H2B.1

1

1

Small-scale

0.479

High

375278

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.479

High

410210

UBC2
Ubiquitin-conjugating enzyme E2 2

1

8

Small-scale

0.479

High

498795

RL4A
Large ribosomal subunit protein uL4A

1

2

Small-scale

0.479

High

600917

UBC1
Ubiquitin-conjugating enzyme E2 1

1

7

Small-scale

0.479

High

604748

HSP74
Heat shock protein SSA4

1

13

Small-scale

0.479

High

604762

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

604763

BMH1
Protein BMH1

1

2

Small-scale

0.479

High

604766

EF2
Elongation factor 2

1

2

High-throughput

0.479

High

604770

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

2

Small-scale

0.479

High

604771

HSP7F
Heat shock protein homolog SSE1

1

15

Small-scale

0.479

High

604776

BMH2
Protein BMH2

1

2

Small-scale

0.479

High

604780

GBLP
Small ribosomal subunit protein RACK1

1

5

Small-scale

0.479

High

604813

RL4B
Large ribosomal subunit protein uL4B

1

2

Small-scale

0.479

High

604816

HUL5
E3 ubiquitin-protein ligase HUL5

1

17

Small-scale

0.479

High

604822

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

604823

CTR9
RNA polymerase-associated protein CTR9

1

1

Small-scale

0.479

High

604824

CDC14
Tyrosine-protein phosphatase CDC14

1

5

High-throughput

0.479

High

604825

ACAC
Acetyl-CoA carboxylase

1

1

Small-scale

0.479

High

343176

TRP
Tryptophan synthase

1

0

Small-scale

0.458

High

404800

RL9A
Large ribosomal subunit protein uL6A

1

0

Small-scale

0.458

High

406791

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

424344

PYR1
Multifunctional protein URA2

1

0

Small-scale

0.458

High

481283

RL2A
Large ribosomal subunit protein uL2A

1

0

Small-scale

0.458

High

481860

RL12B
Large ribosomal subunit protein uL11B

1

0

Small-scale

0.458

High

604749

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

604760

RL5
Large ribosomal subunit protein uL18

1

0

Small-scale

0.458

High

604777

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.458

High

604783

SLI15
Inner centromere protein-related protein SLI15

1

0

Small-scale

0.458

High

604787

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.458

High

604788

LEO1
RNA polymerase-associated protein LEO1

1

0

Small-scale

0.458

High

604796

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.458

High

604815

RTF1
RNA polymerase-associated protein RTF1

1

0

Small-scale

0.458

High

604821

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

0

Small-scale

0.458

High

604831

LTN1
E3 ubiquitin-protein ligase listerin

1

0

Small-scale

0.458

High

604836

DBP9
ATP-dependent RNA helicase DBP9

1

0

Small-scale

0.458

High

604837

UBX5
UBX domain-containing protein 5

1

0

Small-scale

0.458

High

604841

YL054
Uncharacterized transcriptional regulatory protein YLL054C

1

0

Small-scale

0.458

High

604845

RL13A
Large ribosomal subunit protein eL13A

1

0

Small-scale

0.458

High

604811

TCPQ
T-complex protein 1 subunit theta

1

5

High-throughput

0.457

High

339438

CDK1
Cyclin-dependent kinase 1

1

2

Small-scale

0.445

High

560901

EF3A
Elongation factor 3A

1

1

High-throughput

0.437

High

604759

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.437

High

604781

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

604799

PAC2
Protein PAC2

1

5

Small-scale

0.437

High

604805

MPG1
Mannose-1-phosphate guanyltransferase

2

0

Small-scale

0.310

High

604830

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.279

Low

604809

YJN2
Uncharacterized protein YJL132W

1

0

High-throughput

0.269

Low

604834

COQ11
MIOREX complex component 2

1

0

High-throughput

0.269

Low

604838

ACK1
Activator of C kinase protein 1

1

0

High-throughput

0.269

Low

560321

ODPX
Pyruvate dehydrogenase complex protein X component, mitochondrial

1

0

Small-scale

0.249

Low

604756

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

Small-scale

0.249

Low

604779

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

Small-scale

0.249

Low

604782

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.249

Low

604789

KPR2
Ribose-phosphate pyrophosphokinase 2

1

0

Small-scale

0.249

Low

604795

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.249

Low

604797

PTH
Peptidyl-tRNA hydrolase

1

0

High-throughput

0.249

Low

604810

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

604827

GDE1
Glycerophosphocholine phosphodiesterase GDE1

1

0

Small-scale

0.249

Low

604833

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024