HitPredict

Interactor 1: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31300519
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005856 - cytoskeleton
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 581
+	Hs
		428408 TBB5_HUMAN (1-429): 0: 711: 98.37		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1312797 TBB6_HUMAN (1-432): 0: 706: 92.36		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		784079 TBB2B_HUMAN (1-430): 0: 710: 98.14		KPCI_HUMAN (56-568): 6.26e-123: 376: 13.92
+	Hs
		784006 TBB2A_HUMAN (1-430): 0: 707: 97.67		KPCI_HUMAN (56-568): 6.26e-123: 376: 13.92
+	Hs
		428041 TBB5_HUMAN (1-429): 0: 711: 98.37		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		681781 TBB4B_HUMAN (1-427): 0: 711: 100.00		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		983829 TBB3_HUMAN (1-443): 0: 714: 93.23		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		428156 TBB5_HUMAN (1-429): 0: 711: 98.37		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		933766 TBB4B_HUMAN (1-427): 0: 711: 100.00		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		381171 TBB4A_HUMAN (1-427): 0: 706: 98.60		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		983907 TBB6_HUMAN (1-432): 0: 706: 92.36		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		568654 TBB3_HUMAN (1-443): 0: 714: 93.23		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		568659 TBB2A_HUMAN (1-430): 0: 707: 97.67		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		1037238 TBB3_HUMAN (1-443): 0: 714: 93.23		KS6A2_HUMAN (197-576): 4.99e-92: 300: 15.42
+	Hs
		1037241 TBB3_HUMAN (1-443): 0: 714: 93.23		KS6A1_HUMAN (157-555): 9.95e-91: 296: 15.63
+	Mm
		934051 TBB4B_MOUSE (1-427): 0: 711: 100.00		KCC2D_MOUSE (267-505): 9.96e-51: 184: 26.14
+	Mm
		958396 TBB5_MOUSE (1-429): 0: 711: 98.37		KCC2D_MOUSE (267-505): 9.96e-51: 184: 26.14