HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.709

Property	Details
Experiments	28514442, 35271311, 25852190, 22113938
Identification Methods	affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type	physical association, direct interaction, association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 709
+	Hs
		586704 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Hs
		835701 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		SSRP1_HUMAN (1-709): 0: 805: 100.00
+	Sc
		584793 CSK22_YEAST (2-326): 1.7e-120: 354: 59.51		POB3_YEAST (4-504): 0: 541: 29.66
+	Sc
		550117 CSK21_YEAST (1-329): 6.88e-113: 336: 54.32		POB3_YEAST (4-504): 0: 541: 29.66
+	Hs
		934498 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20
+	Hs
		934410 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		CIC_HUMAN (424-708): 7.87e-39: 157: 16.49
+	Hs
		835618 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93
+	Hs
		818783 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15
+	Hs
		586617 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31
+	Hs
		567672 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52
+	Hs
		625125 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		HMGB2_HUMAN (540-698): 5.17e-15: 76.3: 23.53
+	Hs
		449545 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		HMGB1_HUMAN (543-634): 1e-14: 75.5: 34.04
+	Hs
		567641 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		UBF1_HUMAN (416-655): 2.71e-11: 69: 14.52
+	Sc
		514157 HOG1_YEAST (39-323): 2.35e-40: 150: 33.56		NHP6A_YEAST (530-619): 6.02e-28: 109: 35.56