HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27705803, 31076518
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 391 Hs			1 538
+	Hs
		586764 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00
+	Hs
		934219 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		WDR44_HUMAN (53-281): 4.14e-54: 198: 24.46
+	Hs
		792970 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65
+	Hs
		625202 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65
+	Hs
		903116 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		625543 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		586901 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		586813 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		BRWD3_HUMAN (228-450): 4.8e-15: 80.8: 12.86
+	Hs
		835921 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		586657 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		835628 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41