HitPredict

Interactor 1: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Interactor 2: TSYL1 (Q9H0U9)
Testis-specific Y-encoded-like protein 1 (TSPY-like protein 1)
Gene: TSPYL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	28514442, 33961781, 35271311, 32707033
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 391 Hs			1 437
+	Hs
		586975 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		TSYL1_HUMAN (1-437): 0: 540: 100.00
+	Hs
		934468 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		625597 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		586977 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		934104 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		TSPY1_HUMAN (135-429): 6.88e-94: 287: 37.29
+	Hs
		934102 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		SET_HUMAN (185-411): 1.21e-89: 275: 31.78
+	Mm
		1141318 CSK21_MOUSE (1-391): 4.08e-134: 390: 98.72		SET_MOUSE (185-411): 8.8e-91: 278: 33.05
+	Hs
		483598 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		SETLP_HUMAN (185-412): 8.67e-85: 263: 31.22
+	Hs
		934423 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Hs
		625371 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		SET_HUMAN (185-411): 1.21e-89: 275: 31.78
+	Mm
		222429 CSK22_MOUSE (1-334): 4.23e-119: 351: 85.08		SET_MOUSE (185-411): 8.8e-91: 278: 33.05
+	Hs
		876754 CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	Hs
		835669 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		SET_HUMAN (185-411): 1.21e-89: 275: 31.78
+	Dm
		437065 CSK2A_DROME (6-338): 3.31e-130: 378: 87.09		Q24150_DROME (173-408): 1.4e-64: 213: 18.07
+	Hs
		625271 CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	At
		1105859 KSG7_ARATH (39-375): 4.65e-118: 349: 27.95		NAP1A_ARATH (193-408): 2.93e-73: 236: 18.35
+	Hs
		586641 CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	At
		1105876 KSG7_ARATH (39-375): 4.65e-118: 349: 27.95		NAP1B_ARATH (193-408): 1.78e-72: 234: 18.05
+	At
		1105673 KSG7_ARATH (39-375): 4.65e-118: 349: 27.95		NAP1C_ARATH (193-408): 8.46e-71: 230: 18.41
+	Hs
		835612 GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15