Interactor 1: RYR2 (E9Q401)
Ryanodine receptor 2 (RYR-2) (RyR2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2
Interactor 2: CAC1C (Q01815)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (MELC-CC) (Mouse brain class C) (MBC) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: Cacna1c
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.54 | 1.00 | 0.737 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Ca_chan_IQ~EF-hand_7, EF-hand_7~Ion_trans, Ion_trans~Ion_trans, Ion_trans~RR_TM4-6 |
Common GO terms | GO:0005516 - calmodulin binding GO:0006816 - calcium ion transport GO:0006874 - intracellular calcium ion homeostasis GO:0010881 - regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0016020 - membrane and 7 others more... |
Homologous interactions | 10 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024