HitPredict

Interactor 1: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Interactor 2: PCGF1 (Q9BSM1)
Polycomb group RING finger protein 1 (Nervous system Polycomb-1) (NSPc1) (RING finger protein 68)
Gene: PCGF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25281560, 36089195
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 136 Hs			1 259
+	Hs
		952593 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PCGF1_HUMAN (1-259): 4.13e-82: 248: 100.00
+	Hs
		717680 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		717875 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		717557 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		BMI1_HUMAN (30-255): 1.92e-63: 203: 35.29
+	Hs
		935201 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		PCGF6_HUMAN (26-252): 6.21e-45: 156: 36.05
+	Hs
		1086305 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		PCGF6_HUMAN (26-252): 6.21e-45: 156: 36.05
+	Hs
		952606 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		PCGF6_HUMAN (26-252): 6.21e-45: 156: 36.05
+	Hs
		935154 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		1086286 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		952576 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		584928 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RO52_HUMAN (32-226): 9.58e-36: 134: 18.61
+	Hs
		934691 H31_HUMAN (1-136): 2.8e-62: 188: 100.00		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Hs
		952608 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		TRI31_HUMAN (32-246): 2.35e-32: 124: 17.27
+	Hs
		987976 H31T_HUMAN (1-136): 1.27e-61: 187: 97.06		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Hs
		952292 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Hs
		828356 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		RING2_HUMAN (24-259): 7.12e-39: 140: 16.88
+	Hs
		828206 CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00		RING1_HUMAN (24-155): 3.14e-32: 123: 20.59
+	Hs
		282622 H33_HUMAN (1-136): 2.73e-61: 186: 96.32		RNF8_HUMAN (24-130): 3e-10: 61.7: 28.04