Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: TCAM2 (Q8BJQ4)
TIR domain-containing adapter molecule 2 (TICAM-2) (TRIF-related adapter molecule) (Toll/interleukin-1 receptor domain-containing protein)
Gene: Ticam2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 25828701
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0031663 - lipopolysaccharide-mediated signaling pathway
GO:0032755 - positive regulation of interleukin-6 production
GO:0043122 - regulation of canonical NF-kappaB signal transduction
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045087 - innate immune response
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 530
Mm

1 232
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Last updated: 15 Jul 2024