Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: TLR9 (Q9EQU3)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21911421
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006955 - immune response
GO:0007249 - canonical NF-kappaB signal transduction
GO:0032735 - positive regulation of interleukin-12 production
GO:0032755 - positive regulation of interleukin-6 production
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 4 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 530
Mm

1 1032
+ Hs
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Last updated: 15 Jul 2024