HitPredict

Interactor 1: SMAD1 (P70340)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (Dwarfin-A) (Dwf-A) (Mothers-against-DPP-related 1) (Mad-related protein 1) (mMad1) (SMAD family member 1) (SMAD 1) (Smad1)
Gene: SMAD1

Interactor 2: GATA4 (Q08369)
Transcription factor GATA-4 (GATA-binding factor 4)
Gene: GATA4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

The method score is based on:

Property	Details
Experiments	14662776
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus and 9 others more... GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0010628 - positive regulation of gene expression GO:0014898 - cardiac muscle hypertrophy in response to stress GO:0019901 - protein kinase binding GO:0043565 - sequence-specific DNA binding GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0060038 - cardiac muscle cell proliferation GO:1902895 - positive regulation of miRNA transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1	465
Mm

1	441

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024