HitPredict

Interactor 1: EVL (P70429)
Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like)
Gene: EVL

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28469556
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0017124 - SH3 domain binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 414 Mm			1 1730
+	Mm
		1116185 HOME1_MOUSE (1-196): 2.77e-57: 193: 20.10		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Mm
		1116150 HOME2_MOUSE (1-192): 1.07e-55: 189: 20.00		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Rn
		1337547 HOME1_RAT (1-196): 7.51e-57: 192: 19.10		SHAN3_RAT (1-1730): 0: 618: 98.39
+	Hs
		1316291 HOME2_HUMAN (1-192): 1.96e-55: 188: 18.46		SHAN3_HUMAN (1-1730): 0: 601: 95.21
+	Mm
		1116078 HOME3_MOUSE (3-167): 2.72e-39: 145: 20.59		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Hs
		1316292 HOME3_HUMAN (3-167): 2.35e-38: 143: 19.41		SHAN3_HUMAN (1-1730): 0: 601: 95.21
+	Mm
		1116160 PCLO_MOUSE (94-385): 2.25e-09: 61.9: 11.30		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Hs
		1205741 HOME1_HUMAN (1-182): 2.75e-55: 188: 20.54		SHAN2_HUMAN (8-1727): 2.64e-135: 466: 40.52
+	Mm
		1194596 HOME1_MOUSE (1-196): 2.77e-57: 193: 20.10		SHAN2_MOUSE (352-1727): 1.03e-90: 328: 35.55
+	Rn
		1351591 HOME1_RAT (1-196): 7.51e-57: 192: 19.10		SHAN2_RAT (352-1727): 7.52e-89: 322: 35.92
+	Hs
		840528 VASP_HUMAN (1-410): 2.2e-58: 197: 40.00		ANR52_HUMAN (14-494): 3.38e-78: 284: 16.60
+	Dm
		54395 M9PEX1_DROME (1-226): 1.77e-45: 163: 18.57		A1Z9K8_DROME (550-810): 6.28e-60: 230: 29.28
+	Hs
		166898 VASP_HUMAN (1-410): 2.2e-58: 197: 40.00		ANR28_HUMAN (224-592): 3.91e-43: 174: 14.60
+	Mm
		88379 HOME1_MOUSE (1-196): 2.77e-57: 193: 20.10		SHAN1_MOUSE (367-1725): 5.86e-28: 126: 14.36
+	Rn
		1376731 HOME1_RAT (1-196): 7.51e-57: 192: 19.10		SHAN1_RAT (367-1725): 1.25e-27: 124: 14.14
+	Hs
		1191639 SPRE1_HUMAN (2-198): 7.4e-52: 181: 21.29		ASB3_HUMAN (256-378): 4.94e-18: 91.8: 17.97
+	Mm
		88374 HOME3_MOUSE (3-167): 2.72e-39: 145: 20.59		SHAN1_MOUSE (367-1725): 5.86e-28: 126: 14.36
+	Dm
		113976 M9PB30_DROME (95-343): 4.98e-10: 63.9: 7.72		M9PB30_DROME (662-1371): 7.2e-27: 122: 15.27