HitPredict

Interactor 1: E9QAE4 (E9QAE4)
Nuclear receptor-binding SET-domain protein 1
Gene: Nsd1

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SET~WD40
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2691 Mm			1 441
+	Hs
		331862 NSD2_HUMAN (106-784): 0: 614: 17.00		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		1288292 NSD3_HUMAN (131-831): 2.73e-138: 474: 18.43		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		268228 EHMT2_HUMAN (1749-2107): 2.33e-65: 247: 19.08		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		936654 EZH1_MOUSE (1771-2068): 8.13e-68: 247: 22.39		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1142289 EZH2_MOUSE (1771-2068): 2.22e-67: 246: 22.39		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1149787 Q6AXH7_MOUSE (1771-2068): 2.2e-67: 246: 22.39		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268116 EZH2_HUMAN (1771-2068): 2.96e-67: 246: 22.39		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268202 EZH1_HUMAN (1771-2068): 1.82e-67: 246: 22.09		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268290 EHMT1_HUMAN (1781-2098): 1.07e-64: 245: 19.89		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		869800 MSH6_MOUSE (253-532): 1.81e-64: 245: 16.77		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1265660 EHMT2_MOUSE (1749-2107): 1.17e-63: 242: 18.83		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	At
		1319861 ATX1_ARATH (1615-2113): 4.11e-79: 288: 15.37		WDR5A_ARATH (185-440): 5.1e-47: 166: 15.00
+	Hs
		203735 SUV91_HUMAN (1707-2082): 4.11e-90: 302: 21.68		DAW1_HUMAN (292-439): 3.56e-20: 93.8: 13.91
+	Hs
		1288291 SETD2_HUMAN (1790-2120): 3.42e-71: 269: 27.54		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		1281314 EHMT2_HUMAN (1749-2107): 2.33e-65: 247: 19.08		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		855523 MSH6_HUMAN (253-551): 2.79e-65: 247: 18.51		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1080207 EZH2_HUMAN (1771-2068): 2.96e-67: 246: 22.39		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1317584 SETD2_HUMAN (1790-2120): 3.42e-71: 269: 27.54		NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09
+	Hs
		903444 EHMT2_HUMAN (1749-2107): 2.33e-65: 247: 19.08		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		1080462 EZH2_HUMAN (1771-2068): 2.96e-67: 246: 22.39		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97