Protein: MEK1
Meiosis-specific serine/threonine-protein kinase MEK1 (EC 2.7.11.1)

Gene: MEK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 111
UniProt ID: P24719

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004683 - calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

623788

MEK1
Meiosis-specific serine/threonine-protein kinase MEK1

3

17

Small-scale

0.868

High

623804

RAD54
DNA repair and recombination protein RAD54

3

2

Small-scale

0.670

High

412951

KAPB
cAMP-dependent protein kinase type 2

1

13

High-throughput

0.647

High

425597

KAPR
cAMP-dependent protein kinase regulatory subunit

1

13

High-throughput

0.647

High

623817

RIM4
Meiotic activator RIM4

1

3

High-throughput

0.647

High

623839

DOHH
Deoxyhypusine hydroxylase

1

1

High-throughput

0.647

High

419805

SNF1
Carbon catabolite-derepressing protein kinase

1

8

High-throughput

0.646

High

543243

HSC82
ATP-dependent molecular chaperone HSC82

1

20

High-throughput

0.646

High

623793

MIG1
Regulatory protein MIG1

1

0

High-throughput

0.614

High

623846

PCL10
PHO85 cyclin-10

1

0

High-throughput

0.614

High

536245

RED1
Protein RED1

2

0

Small-scale

0.605

High

485655

IF4A
ATP-dependent RNA helicase eIF4A

2

4

High-throughput

0.602

High

588999

HOP1
Meiosis-specific protein HOP1

2

0

Small-scale

0.594

High

510334

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

High-throughput

0.584

High

623823

TEM1
Protein TEM1

1

3

High-throughput

0.579

High

623792

GYS2
Glycogen [starch] synthase isoform 2

2

0

High-throughput

0.577

High

623789

SIS1
Protein SIS1

1

7

High-throughput

0.575

High

623790

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.575

High

623818

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.536

High

623822

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.513

High

623820

NDT80
Meiosis-specific transcription factor NDT80

1

0

Small-scale

0.504

High

562185

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

4

High-throughput

0.501

High

623798

GLNA
Glutamine synthetase

1

1

High-throughput

0.501

High

623803

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

2

High-throughput

0.501

High

623814

ATR
Serine/threonine-protein kinase MEC1

1

16

Small-scale

0.501

High

623833

UAP1
UDP-N-acetylglucosamine pyrophosphorylase

1

1

High-throughput

0.501

High

623850

H3
Histone H3

1

9

Small-scale

0.501

High

623858

SML1
Ribonucleotide reductase inhibitor protein SML1

1

2

High-throughput

0.501

High

341933

ATPB
ATP synthase subunit beta, mitochondrial

1

4

High-throughput

0.500

High

372802

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

1

High-throughput

0.500

High

389231

HXKA
Hexokinase-1

1

4

High-throughput

0.500

High

410918

PDC1
Pyruvate decarboxylase isozyme 1

1

2

High-throughput

0.500

High

424356

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.500

High

498443

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.500

High

555829

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.500

High

560570

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.500

High

562325

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

4

High-throughput

0.500

High

587946

HSP60
Heat shock protein 60, mitochondrial

1

4

High-throughput

0.500

High

623791

CDC48
Cell division control protein 48

1

3

High-throughput

0.500

High

623794

URA7
CTP synthase 1

1

1

High-throughput

0.500

High

623795

BMH1
Protein BMH1

1

13

High-throughput

0.500

High

623816

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.500

High

623821

ARO9
Aromatic amino acid aminotransferase 2

1

1

High-throughput

0.500

High

623832

ERR3
Enolase-related protein 3

1

5

High-throughput

0.489

High

409950

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.480

High

598592

UTR1
NAD(+) kinase

1

0

High-throughput

0.480

High

623799

PAH1
Phosphatidic acid phosphohydrolase 1

1

0

High-throughput

0.480

High

623802

PEP7
Vacuolar segregation protein PEP7

1

0

High-throughput

0.480

High

623805

TYE7
Transcription factor TYE7

1

0

High-throughput

0.480

High

623806

ASH1
Transcriptional regulatory protein ASH1

1

0

High-throughput

0.480

High

623810

RCN1
Calcipressin-like protein

1

0

High-throughput

0.480

High

623815

YHJ3
Uncharacterized protein YHR033W

1

0

High-throughput

0.480

High

623824

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.480

High

623830

SYA
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.480

High

623836

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

623837

IDS2
IME2-dependent-signaling protein

1

0

High-throughput

0.480

High

440856

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

1

0

High-throughput

0.479

High

623841

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

623855

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

546235

CATA
Peroxisomal catalase A

1

1

High-throughput

0.457

High

623797

MLF3
Protein MLF3

1

2

High-throughput

0.457

High

623807

ATG19
Autophagy-related protein 19

1

2

High-throughput

0.457

High

623811

ALY1
Arrestin-related trafficking adapter 6

1

2

High-throughput

0.457

High

623812

ADCS
Aminodeoxychorismate synthase

1

2

High-throughput

0.457

High

623825

HPH2
Protein HPH2

1

1

High-throughput

0.457

High

623829

VHS2
Protein VHS2

1

2

High-throughput

0.457

High

623845

MALX3
Oligo-1,6-glucosidase IMA1

1

1

High-throughput

0.457

High

623852

ATG21
Autophagy-related protein 21

1

1

High-throughput

0.457

High

623854

ARA2
D-arabinose 1-dehydrogenase

1

1

High-throughput

0.457

High

342667

ENO1
Enolase 1

1

5

High-throughput

0.457

High

378293

LEU3
3-isopropylmalate dehydrogenase

1

4

High-throughput

0.457

High

381685

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

2

High-throughput

0.457

High

427181

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

2

High-throughput

0.457

High

516965

INO1
Inositol-3-phosphate synthase

1

1

High-throughput

0.457

High

520918

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

540032

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.457

High

604352

CLH
Clathrin heavy chain

1

1

High-throughput

0.457

High

623860

HSP42
Heat shock protein 42

1

3

High-throughput

0.457

High

477928

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.445

High

490408

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

623800

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

623819

SSZ1
Ribosome-associated complex subunit SSZ1

1

5

High-throughput

0.445

High

623827

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

623809

MID2
Cell wall integrity sensor MID2

1

2

Small-scale

0.439

High

623838

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.407

High

623851

YP077
Uncharacterized protein YPL077C

2

0

High-throughput

0.314

High

623849

SLG1
Protein SLG1

1

0

Small-scale

0.288

High

411217

LEU1
2-isopropylmalate synthase

1

0

High-throughput

0.261

Low

561827

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.261

Low

617230

MBR1
Mitochondrial biogenesis regulation protein 1

1

0

High-throughput

0.261

Low

623796

MLS1
Malate synthase 1

1

0

High-throughput

0.261

Low

623801

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.261

Low

623808

ASK1
DASH complex subunit ASK1

1

0

High-throughput

0.261

Low

623813

SOL2
6-phosphogluconolactonase-like protein 2

1

0

High-throughput

0.261

Low

623828

SIP5
Protein SIP5

1

0

High-throughput

0.261

Low

623831

BUD6
Bud site selection protein 6

1

0

High-throughput

0.261

Low

623834

MIL1
Probable lipase MIL1

1

0

High-throughput

0.261

Low

623835

BUD27
Bud site selection protein 27

1

0

High-throughput

0.261

Low

623840

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.261

Low

623842

ENT3
Epsin-3

1

0

High-throughput

0.261

Low

623843

YJ9S
Uncharacterized protein YJR154W

1

0

High-throughput

0.261

Low

623844

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.261

Low

623847

EFM5
Protein-lysine N-methyltransferase EFM5

1

0

High-throughput

0.261

Low

623848

YN93
Uncharacterized hydrolase YNR064C

1

0

High-throughput

0.261

Low

623853

HED1
Meiosis-specific protein HED1

1

0

Small-scale

0.261

Low

623856

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.261

Low

623859

FRE8
Probable ferric reductase transmembrane component 8

1

0

High-throughput

0.261

Low

367762

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.261

Low

623826

SAHH
Adenosylhomocysteinase

1

0

High-throughput

0.261

Low

623857

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.261

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024