Protein: RPOC
DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta')

Gene: RPOC
Organism: Escherichia coli K-12
Interactions: 115
UniProt ID: P0A8T7

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0000345 - cytosolic DNA-directed RNA polymerase complex
GO:0003677 - DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

495796

RPOB
DNA-directed RNA polymerase subunit beta

6

20

Small-scale

0.946

High

494592

RPOA
DNA-directed RNA polymerase subunit alpha

5

4

Small-scale

0.926

High

365814

RPOD
RNA polymerase sigma factor RpoD

4

7

Small-scale

0.903

High

494659

RPOZ
DNA-directed RNA polymerase subunit omega

3

0

Small-scale

0.809

High

495826

RPOH
RNA polymerase sigma factor RpoH

2

7

High-throughput

0.789

High

495841

RP54
RNA polymerase sigma-54 factor

2

1

High-throughput

0.789

High

495819

NUSA
Transcription termination/antitermination protein NusA

2

0

High-throughput

0.749

High

495820

NUSG
Transcription termination/antitermination protein NusG

2

0

High-throughput

0.749

High

395144

UVRD
DNA helicase II

1

6

Small-scale

0.710

High

495818

FLIA
RNA polymerase sigma factor FliA

1

7

High-throughput

0.691

High

495825

RS1
Small ribosomal subunit protein bS1

1

3

High-throughput

0.691

High

495827

RPOE
ECF RNA polymerase sigma-E factor

1

1

High-throughput

0.691

High

495840

FECI
Ferric citrate uptake sigma factor FecI

1

0

High-throughput

0.656

High

491341

HTPG
Chaperone protein HtpG

2

4

High-throughput

0.628

High

490804

GREA
Transcription elongation factor GreA

1

1

High-throughput

0.625

High

495832

RPOS
RNA polymerase sigma factor RpoS

1

7

High-throughput

0.625

High

495844

GREB
Transcription elongation factor GreB

1

1

High-throughput

0.625

High

495853

RAPA
RNA polymerase-associated protein RapA

1

9

High-throughput

0.625

High

495807

DKSA
RNA polymerase-binding transcription factor DksA

1

0

Small-scale

0.614

High

469899

USG
USG-1 protein

2

1

High-throughput

0.612

High

495854

RL2
Large ribosomal subunit protein uL2

2

2

High-throughput

0.612

High

494040

RS4
Small ribosomal subunit protein uS4

1

0

High-throughput

0.593

High

495810

SSPA
Stringent starvation protein A

1

0

High-throughput

0.593

High

495839

CYSQ
3'(2'),5'-bisphosphate nucleotidase CysQ

1

0

High-throughput

0.593

High

495856

RL24
Large ribosomal subunit protein uL24

1

0

High-throughput

0.593

High

490957

IHFB
Integration host factor subunit beta

2

1

High-throughput

0.588

High

495798

G3P1
Glyceraldehyde-3-phosphate dehydrogenase A

2

1

High-throughput

0.588

High

495811

DBHA
DNA-binding protein HU-alpha

2

1

High-throughput

0.588

High

495803

RLUC
Ribosomal large subunit pseudouridine synthase C

2

0

High-throughput

0.585

High

361743

PHSM
Maltodextrin phosphorylase

2

0

High-throughput

0.563

High

495814

RL16
Large ribosomal subunit protein uL16

2

0

High-throughput

0.563

High

445398

DPO3X
DNA polymerase III subunit tau

1

5

High-throughput

0.536

High

491020

DNAK
Chaperone protein DnaK

1

2

High-throughput

0.536

High

495797

CSPE
Cold shock-like protein CspE

1

2

High-throughput

0.536

High

495801

CSPA
Cold shock protein CspA

1

2

High-throughput

0.536

High

495835

PRIA
Replication restart protein PriA

1

6

High-throughput

0.536

High

495837

LPXD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase

1

2

High-throughput

0.536

High

495838

SYD
Aspartate--tRNA ligase

1

1

High-throughput

0.536

High

495842

RHLE
ATP-dependent RNA helicase RhlE

1

5

High-throughput

0.536

High

495847

YEGD
Uncharacterized chaperone protein YegD

1

8

High-throughput

0.536

High

495851

FTSK
DNA translocase FtsK

1

3

High-throughput

0.536

High

495859

CLPB
Chaperone protein ClpB

1

9

High-throughput

0.536

High

490635

FABA
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase

1

0

High-throughput

0.513

High

492206

PYRG
CTP synthase

1

0

High-throughput

0.513

High

494907

TIG
Trigger factor

1

0

High-throughput

0.513

High

495466

YBED
UPF0250 protein YbeD

1

0

High-throughput

0.513

High

495799

LON
Lon protease

1

0

High-throughput

0.513

High

495809

SDHA
Succinate dehydrogenase flavoprotein subunit

1

0

High-throughput

0.513

High

495817

FKBX
FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.513

High

495822

RSD
Regulator of sigma D

1

0

High-throughput

0.513

High

495830

METH
Methionine synthase

1

0

High-throughput

0.513

High

495831

FECA
Fe(3+) dicitrate transport protein FecA

1

0

High-throughput

0.513

High

495833

SELD
Selenide, water dikinase

1

0

High-throughput

0.513

High

495836

SPEA
Biosynthetic arginine decarboxylase

1

0

High-throughput

0.513

High

495850

USPG
Universal stress protein UP12

1

0

High-throughput

0.513

High

495860

KAD
Adenylate kinase

1

0

High-throughput

0.513

High

495863

VXIS
Prophage excisionase-like protein

1

0

High-throughput

0.513

High

495864

BLUR
HTH-type transcriptional repressor BluR

1

0

High-throughput

0.513

High

495821

YBBO
Uncharacterized oxidoreductase YbbO

1

1

High-throughput

0.489

High

495834

RHSD
Protein RhsD

1

2

High-throughput

0.489

High

365865

DPO1
DNA polymerase I

1

2

High-throughput

0.484

High

382659

RS7
Small ribosomal subunit protein uS7

1

1

High-throughput

0.484

High

473260

DNAJ
Chaperone protein DnaJ

1

2

High-throughput

0.484

High

493210

RS10
Small ribosomal subunit protein uS10

1

3

High-throughput

0.484

High

493360

RS13
Small ribosomal subunit protein uS13

1

2

High-throughput

0.484

High

493859

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.484

High

494241

RS5
Small ribosomal subunit protein uS5

1

2

High-throughput

0.484

High

495800

MREB
Cell shape-determining protein MreB

1

8

High-throughput

0.484

High

495802

RL13
Large ribosomal subunit protein uL13

1

1

High-throughput

0.484

High

495806

CLPA
ATP-dependent Clp protease ATP-binding subunit ClpA

1

10

High-throughput

0.484

High

495823

SPOT
Bifunctional

1

1

High-throughput

0.484

High

495846

CBPA
Curved DNA-binding protein

1

1

High-throughput

0.484

High

495855

RL3
Large ribosomal subunit protein uL3

1

3

High-throughput

0.484

High

495858

RL22
Large ribosomal subunit protein uL22

1

1

High-throughput

0.484

High

495865

KDGR
HTH-type transcriptional regulator KdgR

1

7

High-throughput

0.479

High

384004

RL15
Large ribosomal subunit protein uL15

1

0

High-throughput

0.464

High

444282

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.464

High

449966

HEM3
Porphobilinogen deaminase

1

0

High-throughput

0.464

High

490248

CLPP
ATP-dependent Clp protease proteolytic subunit

1

0

High-throughput

0.464

High

490477

HSCB
Co-chaperone protein HscB

1

0

High-throughput

0.464

High

490701

FIS
DNA-binding protein Fis

1

0

High-throughput

0.464

High

490866

HFQ
RNA-binding protein Hfq

1

0

High-throughput

0.464

High

492578

RL19
Large ribosomal subunit protein bL19

1

0

High-throughput

0.464

High

493136

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.464

High

493466

RS16
Small ribosomal subunit protein bS16

1

0

High-throughput

0.464

High

495643

SYK2
Lysine--tRNA ligase, heat inducible

1

0

High-throughput

0.464

High

495805

YBCJ
Putative RNA-binding protein YbcJ

1

0

High-throughput

0.464

High

495812

HNS
DNA-binding protein H-NS

1

0

High-throughput

0.464

High

495824

RL17
Large ribosomal subunit protein bL17

1

0

High-throughput

0.464

High

495829

IBPA
Small heat shock protein IbpA

1

0

High-throughput

0.464

High

495848

RLMN
Dual-specificity RNA methyltransferase RlmN

1

0

High-throughput

0.464

High

495849

DCTR
HTH-type transcriptional regulator DctR

1

0

High-throughput

0.464

High

495857

RL4
Large ribosomal subunit protein uL4

1

0

High-throughput

0.464

High

495226

YGFB
UPF0149 protein YgfB

1

0

High-throughput

0.458

High

495552

TMAR
Pole-localizer protein TmaR

1

0

High-throughput

0.458

High

495868

YLBH
Putative uncharacterized protein YlbH

1

1

High-throughput

0.442

High

495828

SSB
Single-stranded DNA-binding protein

1

0

High-throughput

0.426

High

420164

ILVA
L-threonine dehydratase biosynthetic IlvA

1

0

High-throughput

0.279

Low

490220

CITX
Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase

1

0

High-throughput

0.279

Low

494774

SMG
Protein Smg

1

0

High-throughput

0.279

Low

495813

YECA
Uncharacterized protein YecA

1

0

High-throughput

0.279

Low

495816

DMA
DNA adenine methylase

1

0

High-throughput

0.279

Low

495852

RATB
UPF0125 protein RatB

1

0

High-throughput

0.279

Low

495861

WCAK
Colanic acid biosynthesis protein WcaK

1

0

High-throughput

0.279

Low

495866

PAOB
Aldehyde oxidoreductase FAD-binding subunit PaoB

1

0

High-throughput

0.279

Low

495870

YDFE
Putative uncharacterized protein YdfE

1

0

High-throughput

0.279

Low

495260

YACL
UPF0231 protein YacL

1

0

High-throughput

0.253

Low

495804

YFDV
Uncharacterized transporter YfdV

1

0

High-throughput

0.253

Low

495808

FOCA
Formate channel FocA

1

0

High-throughput

0.253

Low

495815

CEDA
Cell division activator CedA

1

0

High-throughput

0.253

Low

495843

HOLD
DNA polymerase III subunit psi

1

0

High-throughput

0.253

Low

495845

YJBH
Uncharacterized lipoprotein YjbH

1

0

High-throughput

0.253

Low

495862

YBJX
Uncharacterized protein YbjX

1

0

High-throughput

0.253

Low

495867

FLXA
Protein FlxA

1

0

High-throughput

0.253

Low

495869

YGCP
Uncharacterized protein YgcP

1

0

High-throughput

0.253

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025