HitPredict

Interactor 1: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Interactor 2: DDX1 (Q92499)
ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB)
Gene: DDX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 740
+	Hs
		141299 PABP1_HUMAN (1-448): 6.59e-81: 264: 12.71		DDX3X_HUMAN (1-380): 1.78e-41: 163: 13.47
+	Hs
		141463 PABP4_HUMAN (1-447): 8.2e-81: 264: 13.35		DDX3X_HUMAN (1-380): 1.78e-41: 163: 13.47
+	Hs
		729381 HNRH1_HUMAN (1-449): 3.2e-73: 239: 96.21		DDX17_HUMAN (1-381): 6.43e-36: 147: 11.71
+	Hs
		608517 HNRH2_HUMAN (1-449): 1.1e-74: 242: 100.00		DDX5_HUMAN (1-381): 9.96e-35: 142: 11.45
+	Hs
		608467 HNRH1_HUMAN (1-449): 3.2e-73: 239: 96.21		DDX5_HUMAN (1-381): 9.96e-35: 142: 11.45
+	Mm
		205530 HNRH1_MOUSE (1-449): 6.33e-73: 238: 95.99		Q8BTS0_MOUSE (1-381): 1e-34: 142: 11.45
+	Hs
		807324 HNRPF_HUMAN (1-434): 1.39e-86: 272: 71.95		IF4A3_HUMAN (3-72): 3.94e-11: 67.8: 30.00
+	Hs
		550156 PABP1_HUMAN (1-448): 6.59e-81: 264: 12.71		IF4A3_HUMAN (3-72): 3.94e-11: 67.8: 30.00
+	Hs
		807330 HNRH2_HUMAN (1-449): 1.1e-74: 242: 100.00		IF4A3_HUMAN (3-72): 3.94e-11: 67.8: 30.00
+	Hs
		729164 HNRH1_HUMAN (1-449): 3.2e-73: 239: 96.21		IF4A3_HUMAN (3-72): 3.94e-11: 67.8: 30.00
+	Sc
		403301 PABP_YEAST (103-370): 4.42e-34: 136: 13.87		DED1_YEAST (1-380): 1.94e-35: 144: 13.97
+	Hs
		141495 SART3_HUMAN (2-217): 3.73e-16: 83.3: 23.45		DDX3X_HUMAN (1-380): 1.78e-41: 163: 13.47
+	Hs
		1137122 SART3_HUMAN (2-217): 3.73e-16: 83.3: 23.45		DDX17_HUMAN (1-381): 6.43e-36: 147: 11.71
+	Hs
		141317 NUCL_HUMAN (4-404): 6.64e-09: 60.2: 18.16		DDX3X_HUMAN (1-380): 1.78e-41: 163: 13.47
+	Hs
		729091 HNRH3_HUMAN (10-86): 8.68e-10: 62.2: 33.77		DDX17_HUMAN (1-381): 6.43e-36: 147: 11.71
+	Hs
		608466 HNRH3_HUMAN (10-86): 8.68e-10: 62.2: 33.77		DDX5_HUMAN (1-381): 9.96e-35: 142: 11.45
+	Hs
		608442 NUCL_HUMAN (4-404): 6.64e-09: 60.2: 18.16		DDX5_HUMAN (1-381): 9.96e-35: 142: 11.45
+	Hs
		807425 SART3_HUMAN (2-217): 3.73e-16: 83.3: 23.45		IF4A3_HUMAN (3-72): 3.94e-11: 67.8: 30.00