HitPredict

Interactor 1: CXAR (P78310)
Coxsackievirus and adenovirus receptor (CAR) (hCAR) (CVB3-binding protein) (Coxsackievirus B-adenovirus receptor) (HCVADR)
Gene: CXADR

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0005912 - adherens junction GO:0005923 - bicellular tight junction GO:0030054 - cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 365 Hs			1 1356
+	Hs
		1256876 JAM3_HUMAN (18-296): 2.7e-46: 162: 18.79		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		883798 JAM2_HUMAN (26-296): 8.44e-42: 149: 20.78		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Rn
		1337448 JAM1_RAT (3-305): 6.26e-50: 171: 20.00		PARD3_RAT (1-1356): 0: 685: 89.68
+	Hs
		940598 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		940491 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		LNX2_HUMAN (50-361): 6.83e-21: 101: 11.35
+	Mm
		956922 CXAR_MOUSE (1-365): 2.86e-81: 254: 89.86		LNX2_MOUSE (15-361): 1.42e-19: 97: 11.11
+	Hs
		940410 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		940533 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Mm
		250614 CXAR_MOUSE (1-365): 2.86e-81: 254: 89.86		LNX1_MOUSE (130-385): 1.31e-14: 80.8: 15.33
+	Hs
		940504 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		940406 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		940421 CXAR_HUMAN (1-365): 5.66e-82: 256: 100.00		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Mm
		292319 JAM1_MOUSE (3-305): 2.07e-48: 167: 20.32		MPDZ_MOUSE (452-543): 1.11e-20: 101: 42.39
+	Mm
		1164173 ESAM_MOUSE (3-365): 5.53e-50: 173: 24.75		MAGI1_MOUSE (385-1325): 7.79e-18: 92: 11.39
+	Mm
		936319 DCC_MOUSE (1-365): 1.86e-36: 142: 12.88		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Hs
		990924 JAM3_HUMAN (18-296): 2.7e-46: 162: 18.79		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		883795 JAM2_HUMAN (26-296): 8.44e-42: 149: 20.78		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Mm
		1143386 NRCAM_MOUSE (1-365): 1.19e-26: 113: 11.98		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Mm
		1195001 NRCAM_MOUSE (1-365): 1.19e-26: 113: 11.98		DLG1_MOUSE (274-579): 3.13e-22: 106: 17.50
+	Hs
		1252410 ROBO3_HUMAN (11-362): 1.58e-30: 125: 12.57		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79