Protein: DPB4
DNA polymerase epsilon subunit D (DNA polymerase II subunit D)

Gene: DPB4
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: Q04603

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006261 - DNA-templated DNA replication
GO:0006272 - leading strand elongation
GO:0006338 - chromatin remodeling
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

642074

DPOE
DNA polymerase epsilon catalytic subunit A

16

2

Small-scale

0.762

High

690746

DPB3
DNA polymerase epsilon subunit C

9

1

Small-scale

0.751

High

1046897

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

9

4

Small-scale

0.749

High

665205

DPB2
DNA polymerase epsilon subunit B

8

1

Small-scale

0.748

High

823469

DLS1
Protein DLS1

7

1

Small-scale

0.739

High

917404

ITC1
Imitation switch two complex protein 1

4

2

Small-scale

0.686

High

381631

H2B2
Histone H2B.2

2

5

High-throughput

0.588

High

527639

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

546221

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.552

High

403654

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.513

High

647835

RFA1
Replication factor A protein 1

1

0

High-throughput

0.513

High

646531

RAD53
Serine/threonine-protein kinase RAD53

1

0

Small-scale

0.480

High

594561

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

5

High-throughput

0.479

High

708137

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

734473

BTAF1
TATA-binding protein-associated factor MOT1

1

6

Small-scale

0.479

High

743135

STH1
Nuclear protein STH1/NPS1

1

5

Small-scale

0.479

High

801021

RFC1
Replication factor C subunit 1

1

1

Small-scale

0.479

High

823034

ATAD2
ATPase histone chaperone YTA7

1

1

Small-scale

0.479

High

892815

CTF18
Chromosome transmission fidelity protein 18

1

2

Small-scale

0.479

High

925040

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

932229

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.479

High

963707

H3
Histone H3

1

3

Small-scale

0.479

High

1046895

DPB4
DNA polymerase epsilon subunit D

1

11

Small-scale

0.479

High

448335

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

745870

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

757773

SAS3
Histone acetyltransferase SAS3

1

0

Small-scale

0.458

High

763998

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

849894

IES1
Ino eighty subunit 1

1

0

Small-scale

0.458

High

1046898

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1046900

H2AZ
Histone H2A.Z

1

0

Small-scale

0.458

High

381255

H2B1
Histone H2B.1

1

5

High-throughput

0.445

High

382332

H4
Histone H4

1

3

High-throughput

0.445

High

525102

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

737652

HIR1
Protein HIR1

1

3

High-throughput

0.445

High

781799

SET3
SET domain-containing protein 3

1

2

High-throughput

0.445

High

1035325

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

8

High-throughput

0.445

High

713302

MCM5
Minichromosome maintenance protein 5

1

0

Small-scale

0.426

High

736725

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

820441

RT106
Histone chaperone RTT106

1

0

High-throughput

0.426

High

1042678

SLD5
DNA replication complex GINS protein SLD5

1

0

Small-scale

0.426

High

1046896

CDC45
Cell division control protein 45

1

0

Small-scale

0.426

High

1046899

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

810761

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.407

High

893222

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.279

Low

394893

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025