HitPredict

Interactor 1: RNF4 (P78317)
E3 ubiquitin-protein ligase RNF4 (EC 2.3.2.27) (RING finger protein 4) (Small nuclear ring finger protein) (Protein SNURF)
Gene: RNF4

Interactor 2: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.800

The method score is based on:

Property Details
Experiments 25960396, 19549727
Identification Methods pull down, two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-RING_2
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0070534 - protein K63-linked ubiquitination
GO:0070936 - protein K48-linked ubiquitination
GO:0070979 - protein K11-linked ubiquitination
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 190
Hs

1 201
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024