HitPredict

Interactor 1: F1LUA1 (F1LUA1)
Early endosome antigen 1
Gene: Eea1

Interactor 2: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1450 Rn			1 1383
+	Hs
		435647 EEA1_HUMAN (2-789): 8.93e-33: 141: 12.67		IGF1R_HUMAN (13-1381): 0: 1302: 55.77
+	Hs
		665375 MYH9_HUMAN (490-1440): 1.36e-41: 170: 12.91		EPHA3_HUMAN (661-1320): 4.01e-172: 541: 24.15
+	Hs
		725069 MYH9_HUMAN (490-1440): 1.36e-41: 170: 12.91		ALK_HUMAN (997-1340): 6.12e-71: 264: 41.57
+	Hs
		384384 MYH9_HUMAN (490-1440): 1.36e-41: 170: 12.91		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		725268 MYH10_HUMAN (704-1436): 1.64e-27: 124: 12.25		ALK_HUMAN (997-1340): 6.12e-71: 264: 41.57
+	Hs
		609293 EEA1_HUMAN (2-789): 8.93e-33: 141: 12.67		FGFR3_HUMAN (1016-1288): 2.88e-60: 224: 40.07
+	Hs
		384385 MYH10_HUMAN (704-1436): 1.64e-27: 124: 12.25		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		384856 NUMA1_HUMAN (586-1443): 7.06e-23: 109: 11.85		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		384210 DESP_HUMAN (445-1254): 3.12e-10: 67.4: 19.03		NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95
+	Hs
		338037 MYH9_HUMAN (490-1440): 1.36e-41: 170: 12.91		EGFR_HUMAN (32-308): 1.21e-29: 130: 22.50
+	Hs
		383815 EEA1_HUMAN (2-789): 8.93e-33: 141: 12.67		ERBB2_HUMAN (32-342): 4.75e-18: 92.8: 19.83