HitPredict

Interactor 1: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Interactor 2: DDX50 (Q9BQ39)
ATP-dependent RNA helicase DDX50 (EC 3.6.4.13) (DEAD box protein 50) (Gu-beta) (Nucleolar protein Gu2)
Gene: DDX50

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.697

The method score is based on:

Property Details
Experiments 26167880, 34133714, 32707033, 23602568
Identification Methods enzymatic study, two hybrid, affinity chromatography technology, pull down, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005730 - nucleolus
GO:0005829 - cytosol
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 688
Hs

1 737
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Zm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024