HitPredict

Interactor 1: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Interactor 2: NSRP1 (Q9H0G5)
Nuclear speckle splicing regulatory protein 1 (Coiled-coil domain-containing protein 55) (Nuclear speckle-related protein 70) (NSrp70)
Gene: NSRP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.643

The method score is based on:

Property Details
Experiments 35271311, 23602568
Identification Methods affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation, protein kinase assay
Interaction Type physical association, direct interaction, association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008380 - RNA splicing
GO:0016607 - nuclear speck
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 688
Hs

1 558
+ Hs
+ Hs
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+ Dm
+ Hs

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Last updated: 15 Jul 2024