HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.735

Property	Details
Experiments	26496610, 28514442, 31980649, 26949739, 33961781, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 482
+	Hs
		1038670 TCPH_HUMAN (4-532): 0: 591: 34.08		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		826651 TCPG_HUMAN (3-532): 0: 561: 28.33		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		826803 TCPG_HUMAN (3-532): 0: 561: 28.33		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		821200 TCPE_HUMAN (1-528): 0: 541: 32.29		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		821342 TCPE_HUMAN (1-528): 0: 541: 32.29		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		177367 TCPH_HUMAN (4-532): 0: 591: 34.08		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177257 TCPB_HUMAN (1-535): 0: 586: 100.00		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sc
		693016 TCPB_YEAST (9-532): 0: 566: 65.71		RPD3_YEAST (8-421): 0: 580: 61.48
+	Sc
		693035 TCPH_YEAST (1-532): 0: 559: 33.09		RPD3_YEAST (8-421): 0: 580: 61.48
+	Hs
		177233 TCPG_HUMAN (3-532): 0: 561: 28.33		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177188 TCPA_HUMAN (5-533): 0: 541: 34.30		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		177231 TCPE_HUMAN (1-528): 0: 541: 32.29		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sp
		140638 TCPH_SCHPO (6-533): 0: 576: 33.90		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sp
		140519 TCPG_SCHPO (5-526): 0: 559: 26.74		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		760656 TCPB_YEAST (9-532): 0: 566: 65.71		HOS2_YEAST (10-411): 2.72e-171: 491: 50.00
+	Sc
		792389 TCPH_YEAST (1-532): 0: 559: 33.09		HOS2_YEAST (10-411): 2.72e-171: 491: 50.00
+	Hs
		1306720 TCPH_HUMAN (4-532): 0: 591: 34.08		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		943524 TCPB_HUMAN (1-535): 0: 586: 100.00		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		826927 TCPG_HUMAN (3-532): 0: 561: 28.33		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78
+	Hs
		821448 TCPE_HUMAN (1-528): 0: 541: 32.29		HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78