Protein: HSH49
Protein HSH49

Gene: HSH49
Organism: Saccharomyces cerevisiae S288C
Interactions: 101
UniProt ID: Q99181

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005684 - U2-type spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1037770

CUS1
Cold sensitive U2 snRNA suppressor 1

8

6

Small-scale

0.978

High

1047401

RSE1
Pre-mRNA-splicing factor RSE1

6

2

Small-scale

0.949

High

1065587

RU2A
U2 small nuclear ribonucleoprotein A'

5

3

Small-scale

0.906

High

625154

PRP9
Pre-mRNA-splicing factor PRP9

2

2

High-throughput

0.754

High

892804

SF3B1
U2 snRNP component HSH155

2

9

Small-scale

0.754

High

1059222

PRP11
Pre-mRNA-splicing factor PRP11

2

1

High-throughput

0.754

High

1065125

NCBP2
Nuclear cap-binding protein subunit 2

2

18

High-throughput

0.754

High

1084189

CWC2
Pre-mRNA-splicing factor CWC2

2

9

High-throughput

0.737

High

576030

CYPH
Peptidyl-prolyl cis-trans isomerase

1

3

High-throughput

0.691

High

826534

IST3
U2 snRNP component IST3

1

15

Small-scale

0.691

High

817187

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

4

High-throughput

0.686

High

739291

PRP21
Pre-mRNA-splicing factor PRP21

3

3

High-throughput

0.656

High

865299

LSM8
LSM2-LSM8 complex subunit LSM8

3

9

High-throughput

0.652

High

410423

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.618

High

435472

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.618

High

741205

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

18

High-throughput

0.618

High

743569

RU1A
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.618

High

1025670

NAM8
Protein NAM8

1

14

High-throughput

0.618

High

1057310

RDS3
Pre-mRNA-splicing factor RDS3

2

2

Small-scale

0.611

High

826559

MSL1
U2 small nuclear ribonucleoprotein B''

1

19

High-throughput

0.590

High

796855

SIF2
SIR4-interacting protein SIF2

2

10

High-throughput

0.590

High

863108

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.586

High

739229

PRP19
Pre-mRNA-processing factor 19

2

5

Small-scale

0.571

High

546931

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.536

High

603128

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.536

High

628102

FKBP
FK506-binding protein 1

1

2

High-throughput

0.536

High

744369

CHD1
Chromo domain-containing protein 1

1

7

High-throughput

0.536

High

501749

YSF3
RDS3 complex subunit 10

2

0

Small-scale

0.528

High

1062893

RBX1
RING-box protein HRT1

1

3

High-throughput

0.515

High

676513

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.500

High

1055788

MLC2
Myosin light chain 2

1

1

High-throughput

0.489

High

917721

TOS8
Homeobox protein TOS8

1

0

High-throughput

0.486

High

486375

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.479

High

590760

HSP26
Heat shock protein 26

1

0

High-throughput

0.479

High

433926

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

455345

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

628246

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

4

High-throughput

0.479

High

700170

PRP45
Pre-mRNA-processing protein 45

1

4

High-throughput

0.479

High

702295

YJU2
Splicing factor YJU2

1

1

High-throughput

0.479

High

708670

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

744187

BRR2
Pre-mRNA-splicing helicase BRR2

1

12

High-throughput

0.479

High

751815

PRP8
Pre-mRNA-splicing factor 8

1

3

High-throughput

0.479

High

780245

SN114
Pre-mRNA-splicing factor SNU114

1

5

High-throughput

0.479

High

780874

MUD2
Splicing factor MUD2

1

1

High-throughput

0.479

High

792338

GBLP
Small ribosomal subunit protein RACK1

1

7

High-throughput

0.479

High

820858

RUXG
Small nuclear ribonucleoprotein G

1

5

High-throughput

0.479

High

829969

PRP17
Pre-mRNA-processing factor 17

1

4

High-throughput

0.479

High

933162

RUXF
Small nuclear ribonucleoprotein F

1

2

High-throughput

0.479

High

1033658

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

1043520

CEF1
Pre-mRNA-splicing factor CEF1

1

4

High-throughput

0.479

High

1044957

SYF1
Pre-mRNA-splicing factor SYF1

1

7

High-throughput

0.479

High

1054401

SMD2
Small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.479

High

1084746

CLF1
Pre-mRNA-splicing factor CLF1

1

10

High-throughput

0.479

High

1084899

PRP46
Pre-mRNA-splicing factor PRP46

1

5

High-throughput

0.479

High

918536

RSC1
Chromatin structure-remodeling complex subunit RSC1

1

14

High-throughput

0.464

High

638094

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

796478

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.458

High

1044032

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

1053570

SN309
Pre-mRNA-splicing factor SNT309

1

0

High-throughput

0.458

High

1055579

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

1084901

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

0

Small-scale

0.458

High

559662

GAL3
Protein GAL3

1

1

High-throughput

0.457

High

386937

TBB
Tubulin beta chain

1

1

High-throughput

0.457

High

395050

EF1A
Elongation factor 1-alpha

1

10

High-throughput

0.457

High

531432

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.457

High

621420

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.457

High

644864

CLH
Clathrin heavy chain

1

1

High-throughput

0.457

High

525712

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

742790

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

533426

MITF2
Mitochondrial translation factor 2

1

0

High-throughput

0.438

High

781001

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.438

High

866271

YJ9I
Uncharacterized protein YJR141W

1

0

High-throughput

0.438

High

1050157

TAF7
Transcription initiation factor TFIID subunit 7

1

0

High-throughput

0.438

High

150038

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.437

High

383974

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

436255

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.437

High

442201

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

503327

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

504500

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

512740

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.437

High

514916

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

674922

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.437

High

747671

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

753676

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

874617

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

1046137

RRB1
Ribosome assembly protein RRB1

1

2

Small-scale

0.437

High

445383

CDC31
Cell division control protein 31

1

3

High-throughput

0.417

High

893027

CCH1
Calcium-channel protein CCH1

1

8

High-throughput

0.417

High

1038184

IRC15
Increased recombination centers protein 15

1

2

High-throughput

0.417

High

1085037

YP015
Zinc finger protein YPR015C

1

3

High-throughput

0.417

High

806915

CRG1
Probable S-adenosylmethionine-dependent methyltransferase CRG1

1

0

High-throughput

0.265

Low

368783

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

416498

HXKA
Hexokinase-1

1

0

High-throughput

0.261

Low

797810

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

150345

YP076
Putative uncharacterized protein YPR076W

1

0

High-throughput

0.238

Low

703855

LAC1
Ceramide synthase LAC1

1

0

High-throughput

0.238

Low

803193

YHC6
Uncharacterized protein YHL026C

1

0

High-throughput

0.238

Low

804145

PANE
2-dehydropantoate 2-reductase

1

0

High-throughput

0.238

Low

806076

PEX18
Peroxisomal membrane protein PEX18

1

0

High-throughput

0.238

Low

893041

YG4T
Putative uncharacterized protein YGR226C

1

0

High-throughput

0.238

Low

923304

PDR18
ABC transporter ATP-binding protein/permease PDR18

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025