HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: CDK10 (Q15131)
Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10) (Serine/threonine-protein kinase PISSLRE)
Gene: CDK10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 535 Hs			1 360
+	Hs
		625579 TCPH_HUMAN (4-532): 0: 591: 34.08		CDK2_HUMAN (36-331): 1.52e-139: 399: 43.43
+	Hs
		625349 TCPB_HUMAN (1-535): 0: 586: 100.00		CDK2_HUMAN (36-331): 1.52e-139: 399: 43.43
+	Hs
		943544 TCPB_HUMAN (1-535): 0: 586: 100.00		CD11A_HUMAN (30-353): 4.46e-132: 397: 53.33
+	Hs
		415042 TCPH_HUMAN (4-532): 0: 591: 34.08		CDK1_HUMAN (36-332): 2.51e-130: 376: 39.47
+	Hs
		960322 TCPH_HUMAN (4-532): 0: 591: 34.08		CDK5_HUMAN (36-329): 9.05e-129: 372: 43.39
+	Hs
		625228 TCPG_HUMAN (3-532): 0: 561: 28.33		CDK2_HUMAN (36-331): 1.52e-139: 399: 43.43
+	Hs
		826941 TCPG_HUMAN (3-532): 0: 561: 28.33		CD11A_HUMAN (30-353): 4.46e-132: 397: 53.33
+	Hs
		943194 TCPB_HUMAN (1-535): 0: 586: 100.00		CDK5_HUMAN (36-329): 9.05e-129: 372: 43.39
+	Hs
		573132 TCPA_HUMAN (5-533): 0: 541: 34.30		CDK2_HUMAN (36-331): 1.52e-139: 399: 43.43
+	Hs
		625220 TCPE_HUMAN (1-528): 0: 541: 32.29		CDK2_HUMAN (36-331): 1.52e-139: 399: 43.43
+	Hs
		826623 TCPG_HUMAN (3-532): 0: 561: 28.33		CDK5_HUMAN (36-329): 9.05e-129: 372: 43.39
+	Hs
		414725 TCPA_HUMAN (5-533): 0: 541: 34.30		CDK1_HUMAN (36-332): 2.51e-130: 376: 39.47
+	Hs
		414817 TCPE_HUMAN (1-528): 0: 541: 32.29		CDK1_HUMAN (36-332): 2.51e-130: 376: 39.47
+	Hs
		573225 TCPA_HUMAN (5-533): 0: 541: 34.30		CDK5_HUMAN (36-329): 9.05e-129: 372: 43.39
+	Hs
		821173 TCPE_HUMAN (1-528): 0: 541: 32.29		CDK5_HUMAN (36-329): 9.05e-129: 372: 43.39
+	Hs
		841159 TCPB_HUMAN (1-535): 0: 586: 100.00		CDK7_HUMAN (37-329): 5.56e-77: 242: 42.91