HitPredict

Interactor 1: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Interactor 2: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 535 Hs			1 536
+	Hs
		1306670 TCPH_HUMAN (4-532): 0: 591: 34.08		DNAI2_HUMAN (94-524): 1.05e-93: 299: 24.16
+	Hs
		943469 TCPB_HUMAN (1-535): 0: 586: 100.00		DNAI2_HUMAN (94-524): 1.05e-93: 299: 24.16
+	Hs
		1083362 TCPH_HUMAN (4-532): 0: 591: 34.08		RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16
+	Hs
		1033328 TCPH_HUMAN (4-532): 0: 591: 34.08		DC1I2_HUMAN (42-536): 9.49e-73: 245: 19.69
+	Hs
		943246 TCPB_HUMAN (1-535): 0: 586: 100.00		RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16
+	Hs
		943214 TCPB_HUMAN (1-535): 0: 586: 100.00		DC1I2_HUMAN (42-536): 9.49e-73: 245: 19.69
+	Hs
		148101 TCPH_HUMAN (4-532): 0: 591: 34.08		DC1I1_HUMAN (11-536): 2.11e-70: 239: 18.44
+	Hs
		148061 TCPB_HUMAN (1-535): 0: 586: 100.00		DC1I1_HUMAN (11-536): 2.11e-70: 239: 18.44
+	Hs
		1306645 TCPH_HUMAN (4-532): 0: 591: 34.08		TBL1Y_HUMAN (79-422): 6.5e-49: 178: 9.98
+	Hs
		903467 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65
+	Hs
		943437 TCPB_HUMAN (1-535): 0: 586: 100.00		TBL1Y_HUMAN (79-422): 6.5e-49: 178: 9.98
+	Hs
		903120 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65
+	Hs
		1306704 TCPH_HUMAN (4-532): 0: 591: 34.08		NLE1_HUMAN (10-420): 9.37e-46: 169: 11.16
+	Hs
		943508 TCPB_HUMAN (1-535): 0: 586: 100.00		NLE1_HUMAN (10-420): 9.37e-46: 169: 11.16
+	Hs
		1202777 TCPH_HUMAN (4-532): 0: 591: 34.08		WDR5B_HUMAN (26-340): 6.87e-45: 162: 11.64
+	Hs
		943328 TCPB_HUMAN (1-535): 0: 586: 100.00		WDR5B_HUMAN (26-340): 6.87e-45: 162: 11.64
+	Hs
		1240450 TCPH_HUMAN (4-532): 0: 591: 34.08		POC1A_HUMAN (37-347): 8.43e-35: 137: 12.98
+	Hs
		943355 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1A_HUMAN (37-347): 8.43e-35: 137: 12.98
+	Hs
		943370 TCPB_HUMAN (1-535): 0: 586: 100.00		POC1B_HUMAN (34-263): 1.8e-23: 105: 11.74
+	Hs
		943393 TCPB_HUMAN (1-535): 0: 586: 100.00		FBXW7_HUMAN (37-294): 3.57e-21: 99.3: 11.63