Protein: ZFP91
E3 ubiquitin-protein ligase ZFP91 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ZFP91) (Zinc finger protein 757) (Zinc finger protein 91 homolog) (Zfp-91)

Gene: ZFP91
Organism: Homo sapiens
Interactions: 123
UniProt ID: Q96JP5

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1395474

CRBN
Protein cereblon

3

1

Small-scale

0.840

High

1395486

PRDM5
PR domain zinc finger protein 5

2

14

High-throughput

0.811

High

1331463

ZFP41
Zinc finger protein 41 homolog

2

19

High-throughput

0.783

High

1353584

ZN526
Zinc finger protein 526

2

20

High-throughput

0.783

High

1395476

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

9

Small-scale

0.747

High

1385969

ZN653
Zinc finger protein 653

1

18

High-throughput

0.691

High

1395481

TSYL2
Testis-specific Y-encoded-like protein 2

3

8

Small-scale

0.653

High

1006630

SRPK2
SRSF protein kinase 2

1

10

High-throughput

0.647

High

1273901

BHA15
Class A basic helix-loop-helix protein 15

2

3

High-throughput

0.628

High

1361693

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

2

2

High-throughput

0.628

High

1395494

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

1

High-throughput

0.618

High

401312

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.618

High

891739

GSK3B
Glycogen synthase kinase-3 beta

1

4

Small-scale

0.618

High

1328907

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

18

High-throughput

0.618

High

1395479

KLF16
Krueppel-like factor 16

1

19

High-throughput

0.618

High

419137

H2A1B
Histone H2A type 1-B/E

2

3

High-throughput

0.611

High

643985

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

4

High-throughput

0.611

High

1145327

RNPS1
RNA-binding protein with serine-rich domain 1

2

5

High-throughput

0.611

High

169266

CASQ2
Calsequestrin-2

3

5

High-throughput

0.609

High

1007975

PO6F2
POU domain, class 6, transcription factor 2

2

3

High-throughput

0.606

High

1317040

FAM9A
Protein FAM9A

2

3

High-throughput

0.606

High

1395489

AKIP
Small ribosomal subunit protein mS38

2

0

High-throughput

0.602

High

1395484

LN28A
Protein lin-28 homolog A

2

11

High-throughput

0.601

High

937853

FOXA1
Hepatocyte nuclear factor 3-alpha

2

3

Small-scale

0.584

High

998687

H31
Histone H3.1

2

13

High-throughput

0.584

High

1045648

TF65
Transcription factor p65

2

6

Small-scale

0.584

High

288195

CLC3A
C-type lectin domain family 3 member A

2

2

High-throughput

0.574

High

396721

ESR1
Estrogen receptor

2

14

High-throughput

0.571

High

531127

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

2

High-throughput

0.571

High

1395492

ASC
Apoptosis-associated speck-like protein containing a CARD

2

0

Small-scale

0.559

High

1340312

CEP70
Centrosomal protein of 70 kDa

2

6

High-throughput

0.553

High

1395488

PICK1
PRKCA-binding protein

2

6

High-throughput

0.553

High

586831

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.536

High

658344

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.536

High

686343

RL13
Large ribosomal subunit protein eL13

1

3

High-throughput

0.536

High

809784

RS19
Small ribosomal subunit protein eS19

1

4

High-throughput

0.536

High

854230

KI67
Proliferation marker protein Ki-67

1

2

High-throughput

0.536

High

860887

RS10
Small ribosomal subunit protein eS10

1

5

High-throughput

0.536

High

969369

RS8
Small ribosomal subunit protein eS8

1

1

High-throughput

0.536

High

975865

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.536

High

978661

RL23A
Large ribosomal subunit protein uL23

1

3

High-throughput

0.536

High

979140

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.536

High

984905

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.536

High

1016165

RL19
Large ribosomal subunit protein eL19

1

4

High-throughput

0.536

High

1029361

SET
Protein SET

1

8

High-throughput

0.536

High

1047696

NOTC2
Neurogenic locus notch homolog protein 2

1

20

High-throughput

0.536

High

1061097

SRSF1
Serine/arginine-rich splicing factor 1

1

8

High-throughput

0.536

High

1243844

CTR9
RNA polymerase-associated protein CTR9 homolog

1

2

High-throughput

0.536

High

1260399

H1FNT
Testis-specific H1 histone

1

1

High-throughput

0.536

High

1291809

TSYL5
Testis-specific Y-encoded-like protein 5

1

8

High-throughput

0.536

High

1351007

DDX54
ATP-dependent RNA helicase DDX54

1

4

High-throughput

0.536

High

1390576

NEIL1
Endonuclease 8-like 1

1

3

High-throughput

0.536

High

1395478

DDX50
ATP-dependent RNA helicase DDX50

1

4

High-throughput

0.536

High

1395482

SENP3
Sentrin-specific protease 3

1

3

High-throughput

0.536

High

1395487

DDX21
Nucleolar RNA helicase 2

1

5

High-throughput

0.536

High

1395490

TRM7
tRNA

1

1

High-throughput

0.536

High

1395493

MAGD2
Melanoma-associated antigen D2

1

6

High-throughput

0.536

High

1395495

YBOX2
Y-box-binding protein 2

1

10

High-throughput

0.536

High

1395497

NGN3
Neurogenin-3

1

4

High-throughput

0.536

High

1395498

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

2

High-throughput

0.536

High

1053271

Q05BL1
TP53BP2 protein

1

5

High-throughput

0.515

High

410490

PRM2
Protamine-2

1

0

High-throughput

0.513

High

964141

RL37
Large ribosomal subunit protein eL37

1

0

High-throughput

0.513

High

1203889

NOM1
Nucleolar MIF4G domain-containing protein 1

1

0

High-throughput

0.513

High

657285

KALM
Anosmin-1

1

10

High-throughput

0.489

High

898764

RL14
Large ribosomal subunit protein eL14

1

3

High-throughput

0.489

High

1368712

DLG3
Disks large homolog 3

1

1

High-throughput

0.489

High

1115589

ASPP2
Apoptosis-stimulating of p53 protein 2

1

6

High-throughput

0.481

High

129334

MEN1
Menin

1

2

High-throughput

0.479

High

191050

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

260309

BRD4
Bromodomain-containing protein 4

1

3

High-throughput

0.479

High

315892

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

370758

FOS
Protein c-Fos

1

2

High-throughput

0.479

High

414415

P53
Cellular tumor antigen p53

1

9

High-throughput

0.479

High

474212

NFIC
Nuclear factor 1 C-type

1

14

High-throughput

0.479

High

485340

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

3

Small-scale

0.479

High

504951

H2AB2
Histone H2A-Bbd type 2/3

1

4

High-throughput

0.479

High

668691

APC
Adenomatous polyposis coli protein

1

4

Small-scale

0.479

High

674293

BRD2
Bromodomain-containing protein 2

1

8

High-throughput

0.479

High

810290

RL3
Large ribosomal subunit protein uL3

1

5

High-throughput

0.479

High

887127

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

High-throughput

0.479

High

913006

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

5

Small-scale

0.479

High

981014

H2B1C
Histone H2B type 1-C/E/F/G/I

1

6

High-throughput

0.479

High

986635

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.479

High

1017119

H33
Histone H3.3

1

13

High-throughput

0.479

High

1067606

EP300
Histone acetyltransferase p300

1

7

High-throughput

0.479

High

1087947

NFIA
Nuclear factor 1 A-type

1

13

High-throughput

0.479

High

1124152

E2F2
Transcription factor E2F2

1

2

Small-scale

0.479

High

1137943

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.479

High

1141265

BRD3
Bromodomain-containing protein 3

1

6

High-throughput

0.479

High

1152726

ELF2
ETS-related transcription factor Elf-2

1

3

High-throughput

0.479

High

1156819

E2F4
Transcription factor E2F4

1

2

High-throughput

0.479

High

1255092

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

1314365

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.479

High

1338901

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.479

High

1364209

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

1380717

RL36L
Ribosomal protein eL42-like

1

1

High-throughput

0.479

High

1395475

RING2
E3 ubiquitin-protein ligase RING2

1

17

High-throughput

0.479

High

1395477

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

3

Small-scale

0.479

High

1395480

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

6

High-throughput

0.479

High

1395491

BRPF3
Bromodomain and PHD finger-containing protein 3

1

3

High-throughput

0.479

High

1395496

ZN330
Zinc finger protein 330

1

4

High-throughput

0.479

High

353506

AGR2
Anterior gradient protein 2 homolog

1

3

High-throughput

0.470

High

1270722

Q7KZS0
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.470

High

351151

ECD
Protein ecdysoneless homolog

1

0

Small-scale

0.458

High

1276645

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

47557

RPSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.445

High

883659

CENPA
Histone H3-like centromeric protein A

1

13

Small-scale

0.445

High

1008838

RED1
Double-stranded RNA-specific editase 1

1

7

High-throughput

0.445

High

1367028

ESR2
Estrogen receptor beta

1

14

High-throughput

0.445

High

346197

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

15

High-throughput

0.437

High

477110

IL6RA
Interleukin-6 receptor subunit alpha

1

2

Small-scale

0.437

High

1109652

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

1

Small-scale

0.437

High

1395483

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

483187

CLCA
Clathrin light chain A

1

1

High-throughput

0.407

High

1395485

LUC7L
Putative RNA-binding protein Luc7-like 1

3

0

High-throughput

0.347

High

165817

TR13B
Tumor necrosis factor receptor superfamily member 13B

2

0

High-throughput

0.328

High

402402

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.279

Low

482262

PAEP
Glycodelin

1

0

High-throughput

0.279

Low

652664

GNLY
Granulysin

1

0

High-throughput

0.279

Low

85301

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

0

Small-scale

0.249

Low

1178811

KIZ
Centrosomal protein kizuna

1

0

High-throughput

0.249

Low

1306883

INLR1
Interferon lambda receptor 1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025