Interactor 1: KCJ10 (P78508)
ATP-sensitive inward rectifier potassium channel 10 (ATP-dependent inwardly rectifying potassium channel Kir4.1) (Inward rectifier K(+) channel Kir1.2) (Potassium channel, inwardly rectifying subfamily J member 10)
Gene: KCNJ10

Interactor 2: KCJ11 (Q14654)
ATP-sensitive inward rectifier potassium channel 11 (IKATP) (Inward rectifier K(+) channel Kir6.2) (Potassium channel, inwardly rectifying subfamily J member 11)
Gene: KCNJ11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IRK~IRK, IRK~IRK_C, IRK_C~IRK_C
Common GO terms GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0015272 - ATP-activated inward rectifier potassium channel activity
GO:0034765 - regulation of monoatomic ion transmembrane transport
GO:1990573 - potassium ion import across plasma membrane
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 379
Hs

1 390
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024