HitPredict

Interactor 1: DEN2B (P78524)
DENN domain-containing protein 2B (HeLa tumor suppression 1) (Suppression of tumorigenicity 5 protein)
Gene: DENND2B

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1137 Hs			1 246
+	Hs
		909436 DEN2B_HUMAN (1-1137): 0: 680: 100.00		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		904438 DEN2B_HUMAN (1-1137): 0: 680: 100.00		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		926916 DEN2B_HUMAN (1-1137): 0: 680: 100.00		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683260 DEN2B_HUMAN (1-1137): 0: 680: 100.00		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		646791 DEN2B_HUMAN (1-1137): 0: 680: 100.00		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		683957 DEN2B_HUMAN (1-1137): 0: 680: 100.00		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		904703 DEN2C_HUMAN (149-1136): 0: 568: 43.13		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		982130 DEN2C_HUMAN (149-1136): 0: 568: 43.13		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		683434 DEN2C_HUMAN (149-1136): 0: 568: 43.13		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		646993 DEN2C_HUMAN (149-1136): 0: 568: 43.13		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		909741 MYCPP_HUMAN (590-1129): 2.1e-112: 388: 18.77		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		904778 MYCPP_HUMAN (590-1129): 2.1e-112: 388: 18.77		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		982207 MYCPP_HUMAN (590-1129): 2.1e-112: 388: 18.77		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		927224 MYCPP_HUMAN (590-1129): 2.1e-112: 388: 18.77		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683495 MYCPP_HUMAN (590-1129): 2.1e-112: 388: 18.77		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		647051 MYCPP_HUMAN (590-1129): 2.1e-112: 388: 18.77		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		683454 DEN1B_HUMAN (692-1120): 2.86e-116: 380: 25.34		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		647009 DEN1B_HUMAN (692-1120): 2.86e-116: 380: 25.34		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		684160 MYCPP_HUMAN (590-1129): 2.1e-112: 388: 18.77		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		684129 DEN1B_HUMAN (692-1120): 2.86e-116: 380: 25.34		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20