HitPredict

Interactor 1: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Interactor 2: Z3H7A (Q8IWR0)
Zinc finger CCCH domain-containing protein 7A
Gene: ZC3H7A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30995489
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 4128 Hs			1 971
+	Hs
		944225 PRKDC_HUMAN (1-4128): 0: 6819: 100.00		FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54
+	Hs
		684628 PRKDC_HUMAN (1-4128): 0: 6819: 100.00		STIP1_HUMAN (40-400): 6.8e-30: 127: 10.41
+	Hs
		944386 PRKDC_HUMAN (1-4128): 0: 6819: 100.00		DNJC7_HUMAN (15-196): 1.49e-15: 82.6: 23.91
+	Hs
		1219223 SMG1_HUMAN (3179-4115): 6.6e-124: 444: 16.20		Z3H7A_HUMAN (1-971): 0: 1124: 100.00
+	Hs
		1330398 TRRAP_HUMAN (2754-4128): 0: 828: 15.88		UN45A_HUMAN (26-427): 7.56e-61: 226: 15.14
+	Hs
		1305154 TRRAP_HUMAN (2754-4128): 0: 828: 15.88		DNJC7_HUMAN (15-196): 1.49e-15: 82.6: 23.91
+	Hs
		297116 TRRAP_HUMAN (2754-4128): 0: 828: 15.88		TOM70_HUMAN (2-337): 3.27e-10: 66.1: 6.90
+	Dm
		1358471 TOR_DROME (2776-4127): 0: 727: 18.28		Q9V3E9_DROME (29-378): 4.05e-43: 167: 13.30
+	Hs
		787542 MTOR_HUMAN (2776-4127): 0: 695: 15.99		SGTB_HUMAN (3-276): 5.67e-46: 169: 15.16
+	Hs
		684481 MTOR_HUMAN (2776-4127): 0: 695: 15.99		STIP1_HUMAN (40-400): 6.8e-30: 127: 10.41
+	Hs
		1031592 ATM_HUMAN (3218-4128): 1.84e-158: 557: 19.42		DNJC7_HUMAN (15-196): 1.49e-15: 82.6: 23.91
+	Hs
		858621 ATR_HUMAN (3377-4128): 2.05e-122: 438: 19.28		PPP5_HUMAN (23-214): 3.34e-44: 169: 19.90
+	Hs
		1034841 ATR_HUMAN (3377-4128): 2.05e-122: 438: 19.28		FKBP5_HUMAN (3-225): 1.9e-42: 163: 13.54