HitPredict

Interactor 1: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Interactor 2: NHEJ1 (Q9H9Q4)
Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor)
Gene: NHEJ1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.641

The method score is based on:

Property Details
Experiments 18644470, 30017584, 31548606
Identification Methods enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005958 - DNA-dependent protein kinase-DNA ligase 4 complex
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0033152 - immunoglobulin V(D)J recombination
and 1 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 4128
Hs

1 299
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024