Protein: TPTE
Putative tyrosine-protein phosphatase TPTE (EC 3.1.3.48) (Cancer/testis antigen 44) (CT44) (Transmembrane phosphatase with tensin homology) (Tumor antigen BJ-HCC-5)

Gene: TPTE
Organism: Homo sapiens
Interactions: 130
UniProt ID: P56180

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0005216 - monoatomic ion channel activity
GO:0005829 - cytosol
GO:0006470 - protein dephosphorylation
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

939933

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

2

14

High-throughput

0.754

High

939955

GCN1
Stalled ribosome sensor GCN1

3

16

High-throughput

0.667

High

939967

FACD2
Fanconi anemia group D2 protein

3

0

High-throughput

0.643

High

598048

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

2

5

High-throughput

0.635

High

894652

EMD
Emerin

2

1

High-throughput

0.635

High

627293

AT2B1
Plasma membrane calcium-transporting ATPase 1

2

6

High-throughput

0.621

High

766357

PHB1
Prohibitin 1

2

5

High-throughput

0.621

High

906021

AL3A2
Aldehyde dehydrogenase family 3 member A2

2

3

High-throughput

0.621

High

939914

TPTE
Putative tyrosine-protein phosphatase TPTE

1

15

High-throughput

0.618

High

220889

XPOT
Exportin-T

2

9

High-throughput

0.611

High

273179

CAND2
Cullin-associated NEDD8-dissociated protein 2

2

11

High-throughput

0.611

High

939956

NU205
Nuclear pore complex protein Nup205

2

2

High-throughput

0.611

High

939988

AMFR
E3 ubiquitin-protein ligase AMFR

2

2

High-throughput

0.611

High

939943

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.586

High

939984

SEC63
Translocation protein SEC63 homolog

2

9

High-throughput

0.584

High

939993

5MP1
eIF5-mimic protein 1

2

1

High-throughput

0.584

High

939963

PHB2
Prohibitin-2

2

5

High-throughput

0.567

High

140830

NOP56
Nucleolar protein 56

1

4

High-throughput

0.554

High

189135

IPO8
Importin-8

1

8

High-throughput

0.554

High

773465

COPB2
Coatomer subunit beta'

1

4

High-throughput

0.554

High

934039

XPO2
Exportin-2

1

12

High-throughput

0.554

High

939916

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

3

High-throughput

0.554

High

939917

PRKDC
DNA-dependent protein kinase catalytic subunit

1

4

High-throughput

0.554

High

939924

IMB1
Importin subunit beta-1

1

7

High-throughput

0.554

High

939929

RRP12
RRP12-like protein

1

2

High-throughput

0.554

High

939964

MBB1A
Myb-binding protein 1A

1

3

High-throughput

0.554

High

458348

ADRB2
Beta-2 adrenergic receptor

1

1

High-throughput

0.541

High

484090

PGFRB
Platelet-derived growth factor receptor beta

1

14

High-throughput

0.541

High

641539

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.541

High

710615

EPHA3
Ephrin type-A receptor 3

1

10

High-throughput

0.541

High

939918

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

19

High-throughput

0.541

High

939920

PTK7
Inactive tyrosine-protein kinase 7

1

9

High-throughput

0.541

High

50529

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.536

High

172625

XPO1
Exportin-1

1

14

High-throughput

0.536

High

184419

SURF4
Surfeit locus protein 4

1

1

High-throughput

0.536

High

243916

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

5

High-throughput

0.536

High

245448

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

2

High-throughput

0.536

High

334728

IPO7
Importin-7

1

9

High-throughput

0.536

High

939915

GEMI4
Gem-associated protein 4

1

3

High-throughput

0.536

High

939930

UBR4
E3 ubiquitin-protein ligase UBR4

1

4

High-throughput

0.536

High

939938

MIRO2
Mitochondrial Rho GTPase 2

1

11

High-throughput

0.536

High

939941

NUP93
Nuclear pore complex protein Nup93

1

3

High-throughput

0.536

High

939944

ENAH
Protein enabled homolog

1

3

High-throughput

0.536

High

939947

PCAT1
Lysophosphatidylcholine acyltransferase 1

1

2

High-throughput

0.536

High

939976

WDR6
tRNA

1

12

High-throughput

0.536

High

939977

FANCI
Fanconi anemia group I protein

1

1

High-throughput

0.536

High

939985

DDX20
Probable ATP-dependent RNA helicase DDX20

1

2

High-throughput

0.536

High

939990

DOP1B
Protein DOP1B

1

1

High-throughput

0.536

High

390505

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.530

High

417346

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.530

High

939965

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.530

High

522625

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

0

High-throughput

0.513

High

939927

SMN
Survival motor neuron protein

1

0

High-throughput

0.513

High

939953

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.513

High

939987

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

0

High-throughput

0.513

High

829330

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

4

High-throughput

0.506

High

935827

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

3

High-throughput

0.506

High

939980

HACD3
Very-long-chain

1

2

High-throughput

0.506

High

939991

TLN1
Talin-1

1

8

High-throughput

0.501

High

411664

NTRK1
High affinity nerve growth factor receptor

1

12

High-throughput

0.494

High

640135

EPHA1
Ephrin type-A receptor 1

1

12

High-throughput

0.494

High

710146

EPHA2
Ephrin type-A receptor 2

1

12

High-throughput

0.494

High

939922

TBB3
Tubulin beta-3 chain

1

3

High-throughput

0.494

High

939928

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

1

High-throughput

0.489

High

939951

FACR1
Fatty acyl-CoA reductase 1

1

1

High-throughput

0.489

High

173894

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

5

High-throughput

0.479

High

296474

STAM2
Signal transducing adapter molecule 2

1

7

High-throughput

0.479

High

316373

RMP
Unconventional prefoldin RPB5 interactor 1

1

1

High-throughput

0.479

High

321213

ERLN2
Erlin-2

1

6

High-throughput

0.479

High

611055

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

2

High-throughput

0.479

High

679119

DNJB1
DnaJ homolog subfamily B member 1

1

10

High-throughput

0.479

High

701786

ABCD3
ATP-binding cassette sub-family D member 3

1

2

High-throughput

0.479

High

731132

STIP1
Stress-induced-phosphoprotein 1

1

6

High-throughput

0.479

High

841667

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

5

High-throughput

0.479

High

916634

PPP5
Serine/threonine-protein phosphatase 5

1

10

High-throughput

0.479

High

934338

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

939919

CKAP4
Cytoskeleton-associated protein 4

1

7

High-throughput

0.479

High

939921

TMED1
Transmembrane emp24 domain-containing protein 1

1

1

High-throughput

0.479

High

939939

MIRO1
Mitochondrial Rho GTPase 1

1

9

High-throughput

0.479

High

939940

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

5

High-throughput

0.479

High

939948

DDX54
ATP-dependent RNA helicase DDX54

1

6

High-throughput

0.479

High

939949

IPO4
Importin-4

1

12

High-throughput

0.479

High

939954

UBXN4
UBX domain-containing protein 4

1

2

High-throughput

0.479

High

939957

STAM1
Signal transducing adapter molecule 1

1

4

High-throughput

0.479

High

939958

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.479

High

939962

CLCC1
Chloride channel CLIC-like protein 1

1

1

High-throughput

0.479

High

939970

UN45A
Protein unc-45 homolog A

1

12

High-throughput

0.479

High

939973

RPAP3
RNA polymerase II-associated protein 3

1

9

High-throughput

0.479

High

939974

MT21D
Protein N-lysine methyltransferase METTL21D

1

1

High-throughput

0.479

High

939979

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

1

High-throughput

0.479

High

939986

VATH
V-type proton ATPase subunit H

1

1

High-throughput

0.479

High

939989

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

1

High-throughput

0.479

High

939932

Q6FHY5
MEOX2 protein

1

3

High-throughput

0.470

High

128189

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

High-throughput

0.458

High

250069

ADCY9
Adenylate cyclase type 9

1

0

High-throughput

0.458

High

339457

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.458

High

469041

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.458

High

471636

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

939926

TRAM1
Translocating chain-associated membrane protein 1

1

0

High-throughput

0.458

High

939931

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

0

High-throughput

0.458

High

939959

ASTRA
Protein Aster-A

1

0

High-throughput

0.458

High

939960

VMA22
Vacuolar ATPase assembly protein VMA22

1

0

High-throughput

0.458

High

939968

OSBL8
Oxysterol-binding protein-related protein 8

1

0

High-throughput

0.458

High

939969

S38A1
Sodium-coupled neutral amino acid symporter 1

1

0

High-throughput

0.458

High

939975

VEZA
Vezatin

1

0

High-throughput

0.458

High

939981

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.458

High

893777

MEOX2
Homeobox protein MOX-2

1

2

High-throughput

0.439

High

939923

DSG2
Desmoglein-2

1

4

High-throughput

0.437

High

939925

UBE3C
Ubiquitin-protein ligase E3C

1

13

High-throughput

0.437

High

939935

HEAT3
HEAT repeat-containing protein 3

1

1

High-throughput

0.437

High

939945

UBAC2
Ubiquitin-associated domain-containing protein 2

1

1

High-throughput

0.437

High

939961

NP1L5
Nucleosome assembly protein 1-like 5

1

2

High-throughput

0.437

High

939966

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.437

High

939992

TBL2
Transducin beta-like protein 2

1

3

High-throughput

0.437

High

939950

THEM6
Protein THEM6

1

0

High-throughput

0.279

Low

939972

TRABD
TraB domain-containing protein

1

0

High-throughput

0.279

Low

301381

WFS1
Wolframin

1

0

High-throughput

0.249

Low

332939

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

0

High-throughput

0.249

Low

337709

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.249

Low

939934

TM10C
tRNA methyltransferase 10 homolog C

1

0

High-throughput

0.249

Low

939936

LYRIC
Protein LYRIC

1

0

High-throughput

0.249

Low

939937

RETR3
Reticulophagy regulator 3

1

0

High-throughput

0.249

Low

939942

CBARP
Voltage-dependent calcium channel beta subunit-associated regulatory protein

1

0

High-throughput

0.249

Low

939946

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.249

Low

939952

BRI3B
BRI3-binding protein

1

0

High-throughput

0.249

Low

939971

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low

939978

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

939982

STX18
Syntaxin-18

1

0

High-throughput

0.249

Low

939983

UXT
Protein UXT

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025