HitPredict

Interactor 1: RED1 (P78563)
Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase)
Gene: ADARB1

Interactor 2: STRBP (Q96SI9)
Spermatid perinuclear RNA-binding protein
Gene: STRBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.920

Property	Details
Experiments	32296183, 33961781, 32433965, 24778252, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	A_deamin~dsrm, dsrm~dsrm
Common GO terms	GO:0003723 - RNA binding GO:0003725 - double-stranded RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 741 Hs			1 672
+	Hs
		944763 RED1_HUMAN (1-741): 0: 850: 100.00		ILF3_HUMAN (1-599): 0: 624: 60.13
+	Hs
		944895 RED1_HUMAN (1-741): 0: 850: 100.00		ZFR_HUMAN (5-368): 6.14e-137: 430: 51.51
+	Hs
		944959 RED1_HUMAN (1-741): 0: 850: 100.00		RED2_HUMAN (326-600): 2.01e-57: 208: 27.87
+	Hs
		269692 RED1_HUMAN (1-741): 0: 850: 100.00		PRKRA_HUMAN (355-600): 8.9e-49: 175: 15.81
+	Hs
		944801 RED1_HUMAN (1-741): 0: 850: 100.00		TRBP2_HUMAN (360-613): 5.16e-48: 174: 24.62
+	Hs
		877238 RED1_HUMAN (1-741): 0: 850: 100.00		DSRAD_HUMAN (318-577): 1.93e-23: 108: 21.72
+	Hs
		322475 RED1_HUMAN (1-741): 0: 850: 100.00		STAU1_HUMAN (325-619): 1.99e-19: 94.6: 17.82
+	Hs
		944735 RED1_HUMAN (1-741): 0: 850: 100.00		RED1_HUMAN (449-581): 6.93e-19: 93: 33.08
+	Hs
		944960 RED1_HUMAN (1-741): 0: 850: 100.00		STAU2_HUMAN (416-588): 1.16e-14: 79.5: 19.65
+	Dm
		1228909 ADAR_DROME (18-739): 0: 704: 42.19		Q8MRC7_DROME (326-577): 4.99e-45: 166: 20.13
+	Dm
		93915 ADAR_DROME (18-739): 0: 704: 42.19		F0JAG2_DROME (5-132): 2.7e-41: 161: 41.84
+	Dm
		1228910 ADAT1_DROME (319-737): 2.91e-112: 347: 25.17		Q8MRC7_DROME (326-577): 4.99e-45: 166: 20.13
+	Dm
		1353163 Q9U4F5_DROME (2-300): 7.22e-58: 203: 24.14		Q9TW27_DROME (326-577): 5.01e-45: 167: 20.13
+	Dm
		1228907 Q8MRC7_DROME (2-300): 3.81e-57: 201: 24.14		Q8MRC7_DROME (326-577): 4.99e-45: 166: 20.13
+	Hs
		269745 TRBP2_HUMAN (58-379): 1.3e-50: 182: 21.30		PRKRA_HUMAN (355-600): 8.9e-49: 175: 15.81
+	Dm
		1102403 Q9U4F5_DROME (2-300): 7.22e-58: 203: 24.14		Q2PE36_DROME (512-589): 1.93e-24: 102: 44.87
+	Dm
		1102402 Q9TW27_DROME (2-300): 4.51e-57: 202: 24.14		Q2PE36_DROME (512-589): 1.93e-24: 102: 44.87