HitPredict

Interactor 1: CCL8 (P80075)
C-C motif chemokine 8 (HC14) (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8) [Cleaved into: MCP-2(6-76)]
Gene: CCL8

Interactor 2: CCL8 (P80075)
C-C motif chemokine 8 (HC14) (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8) [Cleaved into: MCP-2(6-76)]
Gene: CCL8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16803905
Identification Methods mass spectrometry studies of complexes
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0001525 - angiogenesis
GO:0002548 - monocyte chemotaxis
GO:0002687 - positive regulation of leukocyte migration
GO:0004672 - protein kinase activity
GO:0005615 - extracellular space
and 24 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 99
Hs

1 99
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024