Interactor 1: M3K9 (P80192)
Mitogen-activated protein kinase kinase kinase 9 (EC 2.7.11.25) (Mixed lineage kinase 1)
Gene: MAP3K9

Interactor 2: M3K21 (Q5TCX8)
Mitogen-activated protein kinase kinase kinase 21 (EC 2.7.11.25) (Mitogen-activated protein kinase kinase kinase MLK4) (Mixed lineage kinase 4)
Gene: MAP3K21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 32707033
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Pkinase, PK_Tyr_Ser-Thr~SH3_9, SH3_9~SH3_9
Common GO terms GO:0004706 - JUN kinase kinase kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006468 - protein phosphorylation
GO:0042803 - protein homodimerization activity
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1104
Hs

1 1036
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Last updated: 15 Jul 2024