HitPredict

Interactor 1: OPA1 (P58281)
Dynamin-like GTPase OPA1, mitochondrial (EC 3.6.5.5) (Large GTP-binding protein) (LargeG) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like GTPase OPA1, long form (L-OPA1); Dynamin-like GTPase OPA1, short form (S-OPA1)]
Gene: OPA1

Interactor 2: OPA1 (P58281)
Dynamin-like GTPase OPA1, mitochondrial (EC 3.6.5.5) (Large GTP-binding protein) (LargeG) (Optic atrophy protein 1 homolog) [Cleaved into: Dynamin-like GTPase OPA1, long form (L-OPA1); Dynamin-like GTPase OPA1, short form (S-OPA1)]
Gene: OPA1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 29222160, 28130547
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Dynamin_N~Dynamin_N, OPA1_C~OPA1_C
Common GO terms GO:0001843 - neural tube closure
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
and 28 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 960
Mm

1 960
+ Dm
+ Sc
+ At
+ At
+ At
+ Mm
+ Hs
+ Sc
+ Hs
+ Hs
+ Rn
+ Sp
+ Hs
+ Hs
+ Hs
+ Mm

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Last updated: 11Aug2025