HitPredict

Interactor 1: PCBP1 (P60335)
Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1)
Gene: PCBP1

Interactor 2: HNRPK (P61979)
Heterogeneous nuclear ribonucleoprotein K (hnRNP K)
Gene: Hnrnpk

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	26336360, 34133714
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	KH_1~KH_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0006397 - mRNA processing GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 356 Mm			1 463
+	Hs
		965686 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00
+	Hs
		965687 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		HNRPK_HUMAN (1-463): 3.38e-139: 409: 100.00
+	Mm
		966015 PCBP2_MOUSE (1-356): 5.63e-96: 291: 79.56		HNRPK_MOUSE (1-463): 3.38e-139: 409: 100.00
+	Hs
		1146899 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16
+	Hs
		1147032 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		IF2B2_HUMAN (6-454): 1.29e-76: 252: 16.16
+	Hs
		1146852 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71
+	Hs
		1147009 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		IF2B1_HUMAN (1-461): 7.01e-66: 223: 14.71
+	Mm
		312357 HNRPK_MOUSE (8-353): 2.85e-69: 225: 22.56		IF2B1_MOUSE (1-461): 9.29e-66: 223: 14.50
+	Mm
		949813 PCBP1_MOUSE (1-356): 1.03e-107: 320: 100.00		IF2B2_MOUSE (2-226): 1.94e-26: 114: 16.16
+	Hs
		944883 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		PCBP4_HUMAN (380-457): 7.64e-20: 93.1: 38.46
+	Hs
		1146670 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		PCBP2_HUMAN (127-222): 1.6e-12: 70.8: 29.17
+	Hs
		1146669 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		PCBP1_HUMAN (7-111): 7.46e-12: 68.5: 14.95
+	Hs
		944807 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		PCBP3_HUMAN (2-111): 7.55e-12: 68.5: 16.67
+	Hs
		903013 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		NOVA1_HUMAN (107-225): 5.15e-11: 66.5: 18.18
+	Hs
		1146761 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		FUBP1_HUMAN (214-460): 4.14e-10: 63.8: 16.73
+	Hs
		135222 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		IF2B3_HUMAN (193-461): 4.23e-09: 60.7: 13.99
+	Mm
		949810 PCBP1_MOUSE (1-356): 1.03e-107: 320: 100.00		Q3TIX6_MOUSE (311-461): 8.04e-09: 60: 18.95
+	Hs
		1146901 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		PCBP2_HUMAN (127-222): 1.6e-12: 70.8: 29.17
+	Hs
		944808 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		PCBP3_HUMAN (2-111): 7.55e-12: 68.5: 16.67