HitPredict

Interactor 1: PCBP1 (P60335)
Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1)
Gene: PCBP1

Interactor 2: IF2B2 (Q5SF07)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: Igf2bp2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	KH_1~KH_1
Common GO terms	GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 356 Mm			1 592
+	Hs
		1146899 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		IF2B2_HUMAN (1-592): 9.94e-148: 440: 92.82
+	Hs
		1147032 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		IF2B2_HUMAN (1-592): 9.94e-148: 440: 92.82
+	Hs
		135222 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		IF2B3_HUMAN (2-592): 1.64e-135: 408: 62.06
+	Hs
		1146852 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		IF2B1_HUMAN (2-592): 6.3e-132: 399: 63.73
+	Hs
		1147009 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		IF2B1_HUMAN (2-592): 6.3e-132: 399: 63.73
+	Mm
		312357 HNRPK_MOUSE (8-353): 2.85e-69: 225: 22.56		IF2B1_MOUSE (2-592): 3.56e-132: 400: 63.23
+	Hs
		1146761 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		FUBP1_HUMAN (408-576): 1.33e-20: 97.9: 22.60
+	Mm
		949810 PCBP1_MOUSE (1-356): 1.03e-107: 320: 100.00		Q3TIX6_MOUSE (189-411): 3.18e-16: 84.1: 19.18
+	Hs
		944883 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		PCBP4_HUMAN (129-393): 1.69e-13: 74.6: 14.20
+	Hs
		1146669 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		PCBP1_HUMAN (491-589): 1.44e-11: 68.1: 16.16
+	Hs
		944807 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		PCBP3_HUMAN (413-520): 2.83e-11: 67.3: 23.42
+	Mm
		949801 PCBP1_MOUSE (1-356): 1.03e-107: 320: 100.00		HNRPK_MOUSE (256-344): 4.46e-11: 67.3: 21.35
+	Hs
		965686 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		HNRPK_HUMAN (256-344): 4.46e-11: 67.3: 21.35
+	Hs
		1146670 PCBP1_HUMAN (1-356): 1.03e-107: 320: 100.00		PCBP2_HUMAN (491-589): 3.01e-10: 64.2: 16.16
+	Hs
		944808 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		PCBP3_HUMAN (413-520): 2.83e-11: 67.3: 23.42
+	Hs
		965687 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		HNRPK_HUMAN (256-344): 4.46e-11: 67.3: 21.35
+	Hs
		1146901 PCBP2_HUMAN (1-356): 2.31e-98: 297: 79.51		PCBP2_HUMAN (491-589): 3.01e-10: 64.2: 16.16
+	Mm
		966015 PCBP2_MOUSE (1-356): 5.63e-96: 291: 79.56		HNRPK_MOUSE (256-344): 4.46e-11: 67.3: 21.35