HitPredict

Interactor 1: SMAD3 (P84022)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)
Gene: SMAD3

Interactor 2: MAN1 (Q9Y2U8)
Inner nuclear membrane protein Man1 (LEM domain-containing protein 3)
Gene: LEMD3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.733

The method score is based on:

Property Details
Experiments 19917253, 26186194, 28514442, 27703004, 33961781, 18729074
Identification Methods pull down, affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005637 - nuclear inner membrane
GO:0031490 - chromatin DNA binding
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 425
Hs

1 911
+ Hs
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+ Hs
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+ Xl
+ Xl
+ Xl
+ Xl
+ Dm
+ Dm
+ Dm
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024