HitPredict

Interactor 1: ARF5 (P84085)
ADP-ribosylation factor 5
Gene: ARF5

Interactor 2: COPG1 (Q9Y678)
Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP)
Gene: COPG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	35844135, 35271311
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Adaptin_N~Arf
Common GO terms	GO:0005794 - Golgi apparatus GO:0006886 - intracellular protein transport
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 180 Hs			1 874
+	Hs
		913217 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		574783 ARF4_HUMAN (1-180): 3.62e-70: 212: 90.00		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		950585 ARF1_HUMAN (1-180): 3.45e-67: 204: 80.56		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		913157 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		574769 ARF4_HUMAN (1-180): 3.62e-70: 212: 90.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		950736 ARF5_HUMAN (1-180): 1.69e-69: 210: 100.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		897411 ARF3_HUMAN (1-180): 4.68e-67: 204: 78.89		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Dm
		778370 ARF4_DROME (1-180): 1.02e-77: 231: 83.89		COPG_DROME (11-874): 0: 719: 60.28
+	Dm
		897447 ARF1_DROME (1-179): 1.52e-66: 202: 79.89		COPG_DROME (11-874): 0: 719: 60.28
+	Hs
		912875 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		AP1B1_HUMAN (14-872): 0: 650: 13.46
+	Dm
		778364 ARF4_DROME (1-180): 1.02e-77: 231: 83.89		Q24253_DROME (14-872): 0: 629: 13.50
+	Hs
		950481 ARF1_HUMAN (1-180): 3.45e-67: 204: 80.56		AP1B1_HUMAN (14-872): 0: 650: 13.46
+	Zm
		30041 B4FB55_MAIZE (8-180): 6.02e-66: 202: 17.42		A0A1D6K3D9_MAIZE (63-873): 0: 651: 14.29
+	Dm
		897433 ARF1_DROME (1-179): 1.52e-66: 202: 79.89		Q24253_DROME (14-872): 0: 629: 13.50
+	Hs
		912839 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		AP2B1_HUMAN (14-871): 0: 591: 12.40
+	Hs
		321520 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		AP2A1_HUMAN (24-874): 0: 582: 14.63
+	Sc
		503061 ARF1_YEAST (1-179): 4.21e-78: 232: 69.83		COPG_YEAST (7-873): 7.79e-169: 516: 32.91
+	Hs
		212615 ARF6_HUMAN (5-179): 5.26e-74: 221: 64.00		AP1G1_HUMAN (17-741): 2.63e-170: 516: 15.52
+	Hs
		212618 ARF1_HUMAN (1-180): 3.45e-67: 204: 80.56		AP1G1_HUMAN (17-741): 2.63e-170: 516: 15.52