Interactor 1: TAF1 (P21675)
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250)
Gene: TAF1

Interactor 2: T2FA (P35269)
General transcription factor IIF subunit 1 (General transcription factor IIF 74 kDa subunit) (Transcription initiation factor IIF subunit alpha) (TFIIF-alpha) (Transcription initiation factor RAP74)
Gene: GTF2F1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.721

The method score is based on:

Property Details
Experiments 8625415, 7590250, 9858607, 9482861, 15053879
Identification Methods enzymatic study, pull down, coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001091 - RNA polymerase II general transcription initiation factor binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
GO:0006366 - transcription by RNA polymerase II
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1893
Hs

1 517
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024