HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: VAV3 (Q9UKW4)
Guanine nucleotide exchange factor VAV3 (VAV-3)
Gene: VAV3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	10523675
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1_1~Ras, PH~Ras, Ras~RhoGEF
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 847
+	Hs
		548678 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		VAV_HUMAN (1-846): 0: 609: 57.31
+	Hs
		855782 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		VAV2_HUMAN (1-846): 0: 574: 50.00
+	Ce
		975575 RAC1_CAEEL (1-191): 4.3e-83: 245: 66.49		VAV_CAEEL (2-847): 1.48e-120: 390: 22.17
+	Hs
		925624 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		ECT2_HUMAN (101-625): 2.68e-83: 287: 18.71
+	Hs
		166482 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		MCF2L_HUMAN (25-656): 1.17e-78: 278: 16.12
+	Hs
		925376 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		FGD5_HUMAN (1-614): 5.83e-77: 275: 13.26
+	Hs
		925527 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		SPT13_HUMAN (135-583): 8.66e-80: 272: 19.05
+	Hs
		925455 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PREX1_HUMAN (144-616): 2.28e-75: 270: 19.65
+	Hs
		925622 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PKHG2_HUMAN (123-811): 2.39e-73: 264: 15.63
+	Hs
		50580 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PKHG3_HUMAN (100-672): 2.7e-73: 263: 16.26
+	Hs
		925649 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		ARHG4_HUMAN (138-579): 1.38e-75: 262: 18.02
+	Hs
		925382 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PREX2_HUMAN (181-616): 3.85e-71: 258: 20.39
+	Hs
		500934 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		MCF2_HUMAN (30-616): 2.14e-72: 257: 15.19
+	Hs
		224711 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		KALRN_HUMAN (152-705): 9.15e-54: 205: 14.14
+	Hs
		279854 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		TRIO_HUMAN (181-666): 3.3e-52: 201: 13.29
+	Hs
		925271 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		ARHG7_HUMAN (747-847): 4.63e-15: 81.8: 27.72
+	Hs
		925289 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		ARHG6_HUMAN (738-847): 4.4e-15: 81.8: 30.00
+	Hs
		580973 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		PLCG1_HUMAN (661-845): 1.02e-14: 80.9: 30.35
+	Gg
		1141019 Q6LC82_CHICK (1-191): 3.6e-82: 243: 71.88		ARHG6_CHICK (737-847): 1.47e-14: 79.8: 24.32
+	Hs
		924448 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		GRB2_HUMAN (793-844): 2.55e-11: 65.9: 40.39