HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: PMYT1 (Q99640)
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)
Gene: PKMYT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 499
+	Hs
		681775 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		AKT1_HUMAN (3-428): 3.62e-133: 395: 20.59
+	Ce
		104472 G5EBV3_CAEEL (2-191): 3.88e-79: 235: 60.00		CST1_CAEEL (77-498): 1.02e-130: 390: 23.54
+	Hs
		564425 RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84		AKT2_HUMAN (3-429): 1.86e-134: 399: 21.35
+	Hs
		568619 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		KAPCA_HUMAN (95-398): 1.19e-126: 374: 21.66
+	Ce
		104466 G5EBV3_CAEEL (2-191): 3.88e-79: 235: 60.00		Q304D8_CAEEL (77-498): 1.72e-127: 379: 23.31
+	Hs
		568605 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		KAPCA_HUMAN (95-398): 1.19e-126: 374: 21.66
+	Hs
		568611 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		KAPCA_HUMAN (95-398): 1.19e-126: 374: 21.66
+	Hs
		436148 RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15		KAPCA_HUMAN (95-398): 1.19e-126: 374: 21.66
+	Hs
		625333 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		CDK2_HUMAN (107-360): 2.87e-100: 305: 27.43
+	Hs
		436162 RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15		CDK2_HUMAN (107-360): 2.87e-100: 305: 27.43
+	Hs
		925778 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		M3K4_HUMAN (80-354): 9.58e-21: 98.2: 32.10
+	Hs
		894645 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		M3K4_HUMAN (80-354): 9.58e-21: 98.2: 32.10
+	Hs
		616691 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		KS6B1_HUMAN (87-293): 8.22e-20: 94.4: 38.25