Protein: ARFG1
ADP-ribosylation factor GTPase-activating protein 1 (ARF GAP 1) (ADP-ribosylation factor 1 GTPase-activating protein) (ARF1 GAP) (ARF1-directed GTPase-activating protein)

Gene: ARFG1, ARFGAP1
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q8N6T3

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

62986

POTEF
POTE ankyrin domain family member F

2

2

High-throughput

0.811

High

1014925

ARF1
ADP-ribosylation factor 1

2

20

Small-scale

0.799

High

783331

TRI23
E3 ubiquitin-protein ligase TRIM23

1

20

High-throughput

0.740

High

170232

AURKA
Aurora kinase A

5

3

High-throughput

0.712

High

1209388

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

3

2

Small-scale

0.692

High

952246

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

3

6

High-throughput

0.675

High

1329716

ASB10
Ankyrin repeat and SOCS box protein 10

1

0

High-throughput

0.663

High

187382

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

3

2

High-throughput

0.662

High

323756

AP2A2
AP-2 complex subunit alpha-2

3

13

High-throughput

0.662

High

344745

AP2A1
AP-2 complex subunit alpha-1

3

13

High-throughput

0.662

High

922593

AP2S1
AP-2 complex subunit sigma

3

3

High-throughput

0.662

High

1329724

AP2M1
AP-2 complex subunit mu

3

1

High-throughput

0.662

High

857054

GSTM5
Glutathione S-transferase Mu 5

3

0

High-throughput

0.638

High

989051

AP2B1
AP-2 complex subunit beta

2

11

High-throughput

0.628

High

1083277

AP1B1
AP-1 complex subunit beta-1

2

10

High-throughput

0.628

High

1097836

STX5
Syntaxin-5

2

5

High-throughput

0.628

High

1235653

NIPBL
Nipped-B-like protein

2

2

High-throughput

0.628

High

247381

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.618

High

827230

ARL1
ADP-ribosylation factor-like protein 1

1

20

High-throughput

0.618

High

791537

SYUA
Alpha-synuclein

2

4

High-throughput

0.606

High

243976

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

2

0

High-throughput

0.602

High

881674

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

2

0

High-throughput

0.602

High

881726

FNTB
Protein farnesyltransferase subunit beta

2

0

High-throughput

0.602

High

1123206

DPYL1
Dihydropyrimidinase-related protein 1

2

0

High-throughput

0.602

High

1234863

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.575

High

1329715

TGFA1
Transforming growth factor-beta receptor-associated protein 1

2

3

High-throughput

0.574

High

950828

KR109
Keratin-associated protein 10-9

1

1

High-throughput

0.573

High

1329728

KRA92
Keratin-associated protein 9-2

1

1

High-throughput

0.573

High

664992

ERD21
ER lumen protein-retaining receptor 1

2

0

Small-scale

0.569

High

1329729

KRA32
Keratin-associated protein 3-2

1

0

High-throughput

0.549

High

651686

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

3

High-throughput

0.541

High

1329721

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.541

High

1329742

RAB23
Ras-related protein Rab-23

1

7

High-throughput

0.541

High

540563

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.536

High

1293371

CARM1
Histone-arginine methyltransferase CARM1

1

3

High-throughput

0.536

High

1329740

COPG2
Coatomer subunit gamma-2

1

12

High-throughput

0.536

High

372582

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.521

High

833424

RGS2
Regulator of G-protein signaling 2

1

0

High-throughput

0.518

High

985766

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.518

High

1241393

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.518

High

570503

GFAP
Glial fibrillary acidic protein

1

4

High-throughput

0.515

High

387854

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

0

High-throughput

0.513

High

1199921

P5CR3
Pyrroline-5-carboxylate reductase 3

1

0

High-throughput

0.513

High

1270374

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.513

High

1279569

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

1

0

High-throughput

0.513

High

1329731

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

6

High-throughput

0.508

High

374765

RASH
GTPase HRas

1

7

Small-scale

0.501

High

384484

CRYAA
Alpha-crystallin A chain

1

5

High-throughput

0.501

High

422598

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

921955

COPA
Coatomer subunit alpha

1

4

Small-scale

0.501

High

829246

RFC3
Replication factor C subunit 3

1

1

High-throughput

0.494

High

1208986

RBG1L
Rab GTPase-activating protein 1-like

1

1

High-throughput

0.494

High

488514

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

0

High-throughput

0.493

High

713120

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.493

High

927421

ATX1
Ataxin-1

1

0

High-throughput

0.493

High

1329720

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

1178850

CF184
Cilia- and flagella-associated protein 184

1

2

High-throughput

0.489

High

1329745

CD2AP
CD2-associated protein

1

18

High-throughput

0.489

High

405509

KITH
Thymidine kinase, cytosolic

1

0

High-throughput

0.486

High

1160514

SMN
Survival motor neuron protein

1

0

High-throughput

0.486

High

370723

FOS
Protein c-Fos

1

1

High-throughput

0.481

High

1329733

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

6

High-throughput

0.481

High

173074

XPO1
Exportin-1

1

10

High-throughput

0.479

High

242285

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

374061

RASN
GTPase NRas

1

8

High-throughput

0.479

High

487533

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

537520

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

582881

EZRI
Ezrin

1

1

High-throughput

0.479

High

695945

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

827847

STAT3
Signal transducer and activator of transcription 3

1

1

High-throughput

0.479

High

862301

YAP1
Transcriptional coactivator YAP1

1

4

High-throughput

0.479

High

920116

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

945044

RAB25
Ras-related protein Rab-25

1

5

High-throughput

0.479

High

951265

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

976416

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.479

High

1049560

1433F
14-3-3 protein eta

1

7

High-throughput

0.479

High

1107926

SQSTM
Sequestosome-1

1

4

High-throughput

0.479

High

1221002

FBW10
F-box/WD repeat-containing protein 10

1

2

High-throughput

0.479

High

1228996

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.479

High

1254646

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.479

High

1276486

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1312555

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

1

High-throughput

0.479

High

1329719

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1329725

BICD1
Protein bicaudal D homolog 1

1

4

High-throughput

0.479

High

1329730

TRI31
E3 ubiquitin-protein ligase TRIM31

1

8

High-throughput

0.479

High

1329732

WWTR1
WW domain-containing transcription regulator protein 1

1

2

High-throughput

0.479

High

47375

A0A6Q8PF08
Peripheral myelin protein 22

1

1

High-throughput

0.470

High

1232332

Q6FG41
Protein c-Fos

1

1

High-throughput

0.470

High

403201

APOB
Apolipoprotein B-100

1

0

High-throughput

0.460

High

210588

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

0

High-throughput

0.458

High

714268

PML
Protein PML

1

0

High-throughput

0.458

High

1085587

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

1289454

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1329714

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1329717

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.458

High

1329723

OPTN
Optineurin

1

0

High-throughput

0.458

High

720394

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

1

Small-scale

0.457

High

564061

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

85287

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

1

High-throughput

0.439

High

1027085

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.439

High

390669

TFR1
Transferrin receptor protein 1

1

2

Small-scale

0.437

High

589162

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

642973

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.437

High

648590

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

768647

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

1096756

RFA4
Replication protein A 30 kDa subunit

1

4

High-throughput

0.437

High

1329738

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

1329743

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.437

High

1243891

AAGAB
Alpha- and gamma-adaptin-binding protein p34

1

0

High-throughput

0.426

High

1329722

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.426

High

1196202

S22A6
Solute carrier family 22 member 6

1

3

High-throughput

0.407

High

1329737

UFSP2
Ufm1-specific protease 2

3

0

High-throughput

0.345

High

1329741

SEC63
Translocation protein SEC63 homolog

3

0

High-throughput

0.345

High

705467

GRN
Progranulin

2

0

High-throughput

0.341

High

1329734

PACC1
Proton-activated chloride channel

2

0

High-throughput

0.328

High

1329739

DIP2B
Disco-interacting protein 2 homolog B

2

0

High-throughput

0.328

High

1329746

SCC4
MAU2 chromatid cohesion factor homolog

2

0

High-throughput

0.328

High

720682

AGTR1
Type-1 angiotensin II receptor

1

0

High-throughput

0.282

High

1217078

RAIN
Ras-interacting protein 1

1

0

High-throughput

0.282

High

376622

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.279

Low

1329736

RIC8A
Chaperone Ric-8A

1

0

High-throughput

0.279

Low

1329744

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.279

Low

387441

APOE
Apolipoprotein E

1

0

High-throughput

0.251

Low

387658

APOC3
Apolipoprotein C-III

1

0

High-throughput

0.251

Low

606915

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

847996

RAD52
DNA repair protein RAD52 homolog

1

0

Small-scale

0.249

Low

965091

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

1226468

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

1329718

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.249

Low

1329727

RDH12
Retinol dehydrogenase 12

1

0

High-throughput

0.249

Low

834995

S19A1
Reduced folate transporter

1

0

High-throughput

0.232

Low

1180289

ATG2A
Autophagy-related protein 2 homolog A

1

0

Small-scale

0.232

Low

1208128

S35D3
Solute carrier family 35 member D3

1

0

High-throughput

0.232

Low

1211175

ODR4
Protein odr-4 homolog

1

0

High-throughput

0.232

Low

1329726

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low

1329735

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025