HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: ZCH18 (Q86VM9)
Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1)
Gene: ZC3H18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	29298432, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 164 Hs			1 953
+	Hs
		1084321 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		992832 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1028718 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		267016 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		853937 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		516580 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		ZCH18_HUMAN (1-953): 3.56e-83: 290: 100.00
+	Hs
		1084451 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		853964 NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14		MINT_HUMAN (8-923): 2.4e-20: 99.8: 10.24
+	Hs
		952179 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		992995 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		1084330 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		1028876 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		267100 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		SRRM2_HUMAN (7-950): 3.04e-18: 92.9: 11.64
+	Hs
		703409 CSTF2_HUMAN (10-110): 1.87e-25: 103: 25.47		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		952031 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		992840 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		1028727 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		SRRM1_HUMAN (39-841): 2.51e-14: 79.8: 12.14
+	Hs
		1031405 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		TITIN_HUMAN (139-952): 5.65e-14: 79: 9.54
+	Hs
		992771 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		TRIPC_HUMAN (539-925): 2.98e-10: 66.6: 17.28
+	Hs
		992772 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		MDC1_HUMAN (9-950): 1.49e-09: 64.4: 9.73